Marys Medicine

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030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 1 have the pleasure of presenting my experience with Skin Tech products through this brochure. Some of them are preparations for chemical peelings and others are for the daily treatment that patients must apply in order to improve and/or maintain the excellent results attained quickly through the Skin Tech products appeared gradually to cover the aesthetic needs of patients and doctors, currently from over fifty countries throughout the world. Skin Tech progressively adapted to numerous indications for all types of skin, thanks to the help of a great many doctor friends who shared with me their experiences and knowledge, allowing me to improve Skin Tech product formulas until they reached their present state.
This brochure thus reveals a large part of this shared international experience resulting from the joint work of numerous doctors, their minds having no limits but the desire to improve their daily work tools and help their patients, who appreciate the efforts of an interested doctor in making them look better.
Hence my peeling application protocols were followed throughout the world, commented on by doctors, dermatologists, surgeons and other specialists.
They were modified and adapted until they reached its current state. We will remain in constant contact in order to ensure that Skin Tech products improve year after year.
This collaboration allowed me to quickly comprehend the importance of the daily care that complements the effects of the peelings, improves them and maintains them for a long time. For this reason, Skin Tech has developed a line of creams especially designed for use both during treatment, when the skin is highly sensitive, and after the peelings, for daily skin care.
 In the present brochure, the recommendations and warnings that doctors should give their patients are emphasised (and repeated many times). Some of the most important are those of adopting measures of protection against sunlight and following the daily care measures indicated by the doctor.
I have not attempted to write a treatise on dermatology, nor even to write a text on aesthetic medicine, but rather contribute towards ensuring that Skin Tech products provide you with the same results that I have obtained with my patients.
Philippe Deprez MD



030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 2 TCA + AHA + Antioxidants Used in more than 50 Superficial or Medium-depth Peel countries, and on all photo Sustained Dermal Stimulation and ethno types, Easy TCA is Social Life: Allowed (Basic Protocol) considered to be the safest and easiest trichloroacetic acid peel.
Easy TCA Classic Kit 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 3 The Classic Kit of Easy TCA, includes:Twelve ampoules of base solution: Post-Peel Mask is applied immediately Easy TCA Combined with Other saponified and adjuvated solution of after the peeling, when the desired Applied according to different protocols, alpha hydroxy acids and vitamins.
frosting has appeared.
Easy TCA allows for a wide spectrum of depths and actions. Easy TCA can With Deeper Peelings Injection of TCA in the base solution be applied to both face and/or body.
Easy TCA can be used in combination transforms it into the Easy TCA 15%m/m peeling solution, pH <1. (Adequate quantities of TCA to be added: see The Basic Protocol can be used -Papillary dermis: Unideep, TCA 23% information’s in the Easy TCA kit.) Each Base solution + Trichloroacetic acid = m/m + Post-Peel Mask -Reticular dermis: Only Touch (local), ampoule contains enough base solution Easy TCA 15% m/m peeling solution to do a full face and neck treatment on -Deep phenol peel: Lip & Eyelid one patient.
Post-Peel Mask pH 6.5-7 (Not a - Photoageing, smoker's skin Three tubes of Post-Peel Mask: with neutralising cream) - First wrinkles, keratosis antioxidant active ingredients, vitamins, Both face and/or body: hands and Combined With Other trace elements, fatty acids, growth factor, forearms, neck and décolleté.
and antityrosinase effect. Post-Peel Mask formulation warrants a very The Abrasive Protocols can be -Laser, flash lamp, electric depilation, important part of the beneficial effects on the skin.
-Telangiectasy treatment - Pilar keratosis - Very damaged décolleté





030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 4 Material and Methods Preparing Easy TCA Peeling Solution Easy TCA base solution phial
Small glass container
1 ml syringe
50 % M/M trichloro acetic acid
The chemist should prepare the following R/TCA crystals 25 g + distilled water 25 g to make 50 g of a 50% m/m TCA Solution.
(included in the kit) (included in the kit)


030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 5 Easy TCA Peeling Solution: Preparation Patient Preparation No preparation is needed before applying Easy TCA.
It is not necessary to clean, degrease or to eliminate makeup from the skin, except in the case of impermeable silicone makeup.
For cleansing, use Skin Tech Pre-Peel Break open one of Pour the content into Syringe 0.7 ml of Add 0.7 ml of 50% m/m the base solution the small glass container 50% m/m trichloro TCA solution to the base (directly or using a syringe).
acetic acid (TCA).
The Easy TCA peeling solution is now ready to use.
Base Solution + TCA = Easy TCA Peeling Solution 15% m/m pH<1
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 6 Applying the Easy TCA Peeling Solution Gradually apply as many coats of peeling solution as required for the first spots of frosting to appear. Let each coat dry before applying the next. The number of coats varies depending on skin type.
Coats required for frosting spots to appear (indicative reference) Moisten two cotton swabs with Easy TCA solution.
Clouds of frosting will appear if additional Thin skin, or skin treated coats are added after the appearance with tretinoin and glycolic of the first pinpoints of frosting. Once acid (or other AHA) the first pinpoint of frosting appears, apply the Post-Peel Mask immediately.
Thick and oily skin Remove excess product by pressing the swab against the neck or edge of the 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 7 Post-Peel Mask Application To apply the right quantity of Post-Peel Mask, use the card included in the Easy Physicians should advise patients against washing the treated zone until the next morning. Patients should use The lines help to measure the quantity a gentle soap and rinse well with water.
of Post-Peel Mask.
Physicians should advise patients One side of the card shows icons.
against wearing metallic jewellery after One thin line is equivalent to about 0.5 g peeling (48 hours at least).
It shows the quantities to be applied on of Post-Peel Mask.
different parts of the body.
According to the Easy TCA Basic Two thin lines are equivalent to 1 g.
The other side shows lines.
Protocol, the peeling session ends once Four lines are equivalent to 2 g of Post- the Post-Peel Mask has been applied.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 8 Patients should begin to apply the treated areas, or those areas in which Easy TCA: A Flexible prescribed Skin Tech daily care products desquamation is taking place.
Peeling Tool. A Wide Range the first day after the Easy TCA peeling.
of Depths and Effects.
Skin Tech daily care products have been During the medical peeling procedures, specifically formulated to be used after, patients should refrain from using any Various protocols can be or in combination with, peeling cosmetic peeling or exfoliating products.
performed with the Easy TCA kit.
procedures. This is not the case of most An intraepidermic or other type of peel cosmetics products on the market. It is can be done, up to the basal layer. This not advisable to use certain common In very sunny regions, it is mandatory procedure does not interrupt normal cosmetics products, which could cause to take extra steps to protect the skin social life.
problems when applied on recently peeled skin.
against harmful sun exposure. For photosensitive skin, use Blending Easy TCA also allows for a deeper peel, Bleaching Cream twice a day, beginning up to the papillar dermis, as explained Once the daily care cream has been the first day after the first peeling session.
in the instructions for use.
applied, always use sun protection (in addition to makeup if desired).
If the appropriate steps are taken, Easy TCA can be safely used in any season With Easy TCA, physicians can always and on all phototypes.
reach the desired depth.
Avoid sun exposure during the peeling procedure and for six weeks afterwards.
Physicians should advise patients against touching or scratching the 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 9 Intraepidermic peel Erythema without frosting 4 peels: one per week* Peel to the basal layer 4 peels: one per week* Peel to the Grenz zone 4 peels: one per week* Intrapapillary dermis peel Pink, white, even frosting Repeat after one month Deep peel after sand abrasion Phenol-like skin liquefaction Repeat after one month and with occlusion to treat stretch marks or scars 24 hours after the peeling *It is mandatory to perform four Easy TCA peeling sessions, one per week. Physicians must be aware that performing only one peel can increase the risk of pigmentary rebound.
Uniform frosting white pinkish 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 10 Skin Tech Product to be Applied Sagging flaccid skin Twice a day: morning and evening Actilift with dimethylaminoethanoL During the day (whole area) Vit.E Anti-oxydant Ageing skin <40-45 At night (whole area) Re-Nutriv ACE Lipoic Complex During the day (whole area) Ageing skin >40-45 The morning after the Easy TCA peeling At night (whole area) Re-Nutriv ACE Lipoic Complex procedure, patients can cleanse their During the day (whole area) skin with a gentle soap or a similar At night (only on acne lesions) Daily and until the next peeling session, During the day (whole area) Blending Bleaching Cream patients should continue using the + SPF 20-60 sun protection at prescribed Skin Tech daily care cream.
Avoid sun exposure Blending Bleaching Cream At night (only for hyper-pigmentation) Morning, evening, night Vit. E Anti oxydant 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 11 GRAPHIC: PEELING REPETITION Regeneration cycle Four peeling sessions along with the use of daily care creams, constitute a regeneration cycle.
The frequency of repetition depends on On the face the basic protocol should be repeated once a week the protocol.
On the face, the basic protocol should be repeated once a week.
2 weeks 2 weeks 2 weeks To maintain the results, apply one On the rest of the body should be regeneration cycle a year, combined repeated each two weeks.
with daily care creams.
The abrasive protocol should be repeated once a month, according to On the rest of the body should the skin condition.
be repeated each two weeks The regeneration cycle can be repeated up to three times after six weeks of use of Skin Tech daily care creams. The physician should decide the number of additional sessions, according to the 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 12 Photoageing and smoker´s skin The Easy TCA Basic Protocol can be care creams are specifically designed used to fight the most noticeable signs for this purpose, and can be used for of photoageing, such as wrinkles and dry and uneven skin. To treat these signs It is important to protect the skin against of photoageing, physicians should apply sun exposure. According to skin type, the Basic Protocol according to the SPF 20-60 should be used. Sun instructions for use.
protection should be applied over the daily care cream. Apply the sun The Basic Protocol peeling should be protection between 11 am and 1 pm to repeated four or five times, once a week, avoid the harmful effects of sun for six weeks. The four peeling sessions, exposure (UVA and UVB).
along with the use of daily care creams, Regeneration cycle to fight signs of constitute a regeneration cycle.
Daily Care Creams photoageing = four or five peeling sessions + six weeks of daily application For patients under 40-45: Apply Vit. E of care creams.
Anti oxydant in the morning. In the The cycle may be repeated up to three evening, apply Re-Nutriv ACE Lipoic times, if necessary. Afterwards, one cycle a year is required to maintain the The peeling sessions are the basis on which healthy skin regeneration begins.
For patients over 40-45: Apply DHEA To fight signs of photoageing, however, PHYTO in the morning, and Re-Nutriv it is necessary to combine the peeling ACE Lipoic Complex in the evening.
procedures with Skin Tech daily care products. Skin Tech daily 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 13 Melasma and Lentigo Extensive Hyperchromia (Melasma)Use the appropriate protocol according Repeat the peeling procedure four (five) Visible improvement after the second to the type of lesion. Extensive (Melasma times, one a week.
or third Easy TCA: the melanin was at type) or localised hyperchromia (Lentigo Use the Easy TCA Basic Protocol: apply the level of the epidermis. In general, a type) can be treated.
the Easy TCA peeling solution to obtain Daily Care During and After Easy single regeneration cycle will be frosting points. Once the frosting points are visible, apply Easy TCA peeling solution on the blemishes only, to obtain Apply Blending Bleaching Cream twice Maintain the results using Blending an irregular “cloudy” frosting. Then apply a day. In the morning, apply it on the Bleaching Cream twice a day, and a the Post-Peel Mask.
whole area; in the evening, apply it to sun protection cream (SPF 20-60). Apply the blemishes only. Begin applying the the Blending Bleaching Cream, starting False Pigmentary Rebound Blending Bleaching Cream the morning the day after the first peeling procedure.
Use the Blending Bleaching Cream for after the first Easy TCA peeling. Use These “cloudy” areas will become the Blending Bleaching Cream for at at least six weeks after the end of the dehydrated and may appear darker on least six weeks after the end of the peeling procedures.
the second and third days. This is not peeling procedures (preferably for six pigmentary rebound, but simply Insufficient improvement after the epidermal desiccation. The area will second or third peeling: the melanin must be considered to be deep. The quickly slough off.
treatments will have to be repeated and used in combination with the Blending According to the skin’s condition, after Bleaching Cream and total sun two peelings the physician may evaluate protection, or in combination with Only the future progress of the peeling 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 14 Melasma and Lentigo Resistant Hyperchromia Physicians should have patience with this process, as keratosis is not easily For hyperchromia that resists other treatments, prepare the skin by applying the Blending Bleaching Cream twice a Even out the treatment by applying an day for the two weeks leading up to the Easy TCA (Basic Protocol) over the area Post-Peel Caution first Easy TCA peeling.
as a whole, including the places where Patients must refrain from scratching Only Touch has been applied. Using Inform patients that the crusts produced these areas, as this could result in Localised Hyperchromia Easy TCA after Only Touch limits the by Only Touch treatment are brown.
permanent scarring.
risk of pigmentary rebound, which can They last for about 12 days and leave Patients must wear total sun block and result from using Only Touch on its own.
an erythema; this does improve, but can avoid intense light. Preventive or curative take three weeks to three months to measures must be taken in cases of Combine Easy TCA + Only Touch disappear. Patients must refrain from persistent erythema or pigmentary scratching these areas, as this could Applying Only Touch result in permanent scarring.
Using a cotton bud or wooden toothpick, apply Only Touch carefully, precisely on the blemishes or keratosis. A noticeable frosting will appear.
How quickly it appears will depend on the permeability of the skin or the thickness of the keratosis.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 15 Easy TCA + Only Touch repetition Inter and post peeling The next day after the first peeling procedure begin applying Blending Bleaching Cream. In the morning, apply Blending Bleaching Cream, on the whole region. In the evening apply just on the lentigos. Apply Blending Bleaching Cream during at least six weeks after the final peeling, better during six month Daily Care Creams: Combine with an For patients under 40-45: Apply Vit.E Anti-oxydant in the morning. In the evening, apply Re-Nutriv ACE Lipoic For patients over 40-45: Apply DHEA On the rest of the body PHYTO in the morning, and Re-Nutriv ACE Lipoic Complex in the evening.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 16 Easy TCA Scalp Protocol to Treat Blemishes and/or Keratosis Scalps with sparse hair are usually Scalp Preparation Local Anaesthesia susceptible to accelerated photoageing, with the appearance of blemishes and -Clean the skin with Skin Tech Pre- If it seems that more than three coats Avoid sunlight entirely. Apply SkinTech keratosis. These problems can be will be necessary, physicians should Vit. E Anti-oxydant, four or five times a -Rinse with water assess the suitability of truncal blocks.
Leave to dry completely between each -Disinfect with alcohol coat. Ventilate or cool with a 3M Cold -Degrease with acetone Pack, to soothe the pain caused by the -Leave acetone to evaporate peeling solution.
Avoid sunlight entirely. Apply DHEA PHYTO in the morning, and Re-Nutriv Applying Easy TCA ACE Lipoic Complex in the evening. For (Also with Unideep) hyperchromia, apply Blending Bleaching Desquamation will occur after one week Cream twice a day, in the morning and treated using the following protocols for Treat the whole area affected by at least and will last for 4-5 days (see extensive hyperchromia or keratosis, or blemishes and/or keratosis, not just the for localised hyperchromia or keratosis.
localised lesions. Apply a sufficient When necessary, apply Vaseline to number of coats of Easy TCA Peel solution for an even frosting of the Repeat the treatment four times at two- A light abrasion beforehand – or an perikeratosic skin. Sometimes up to five week intervals if desquamation has intraepidermal Erbium laser – can coats are required. Wait until each coat significantly accelerate penetration of is dry before applying the next coat.
the Easy TCA Peel solution. In this case, Ventilate or refresh, to provide pain relief.
topical post-abrasion anaesthesia is After 4 peelings Full frosting required Use 2% lidocain with adrenalin.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 17 Easy TCA Protocol for Extensive Scalp Hyperchromia or Keratosis Patience is required, since the frosting Easy TCA Protocol for Localised Post-Peel Caution takes much longer to appear.
Scalp Hyperchromia or Keratosis When non-keratosic skin has whitened, Inform patients that the crusts produced enough Easy TCA Peel solution has Applying Only Touch by Only Touch treatment are brown.
been applied. When this skin area is Using a cotton bud or wooden toothpick, They last for about 12 days and leave pinched, a fine wrinkling can be seen, apply Only Touch carefully, precisely on an erythema; this does improve, but can showing that the papillary dermis (photo) the blemishes or keratosis. A noticeable take three weeks to three months to has been reached.
frosting will appear. How quickly it appears will depend on the permeability Patients must refrain from scratching After the frosting, apply the Post-Peel of the skin or the thickness of the these areas, as this could result in Mask and massage it in. The peeling permanent scarring.
procedure is now complete. Prescribe Total sun block, and avoidance of Keratosis is not easy permeable. More a moderate painkiller.
time is required for the Easy TCA Physicians should have patience with intense light.
solution to pass through them.
this process, as keratosis is not easily Patients must wear total sun block and avoid intense light.
Preventive or curative measures must Even out the treatment by applying an be taken in cases of persistent erythema Easy TCA (Basic Protocol) over the area or pigmentary rebound.
as a whole, including the places where Only Touch has been applied. Using Easy TCA after Only Touch limits the risk of pigmentary rebound, which can result from using Only Touch on its own.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 18 Easy TCA Acne Protocols These Easy TCA protocols explain only + 6 weeks of Purifying Cream = the methods for using the peeling regeneration cycle which can be procedures on cases of acne. Easy TCA repeated up to three times peelings are cosmetic treatments that Apply Purifying Cream twice a day, from can improve the appearance of acne, the first day after the peeling procedure, and can be beneficial in combination and at least six weeks after the last Researchers recognise that the first with clinical and dermatological peeling, better much longer.
goal in fighting acne is to prevent the exfoliated keratinocytes from sticking Fighting Acne from its Molecular When the Easy TCA peeling solution is Easy TCA Acne Protocols are not The challenge is to normalise the applied to acneic skin, a noticeable intended to substitute the contents of keratinisation/exfoliation rate in a way frosting should appear around the acne any clinical dermatology guide for acne Physicians agree that acne etiology is that is healthy.
lesions. This effect is irrelevant; it is treatment. To treat acne, physicians complex. To date, experts have been Purifying Cream includes a precursor merely related to the skin’s increased must proceed according to their unable to pinpoint one isolated cause of tretinoin, with a clinically-proven permeability around the acne lesions.
experience, knowledge and professional or find a panacea.
stimulating effect on the desquamation Dermatologists also stress that any To improve and ensure peel results, the successful treatment of acne includes peeling sessions must be repeated. For a multifaceted attack: considering each treating acne, four peeling sessions are individual patient, and several well- required: one a week, followed by six known factors such as the weeks of rest.
desquamation rate, bacterial infection, This cycle may be repeated if necessary.
drainage of the follicular pore, Combine Easy TCA with Purifying inflammation, and sebum production.
Cream: four Easy TCA peels 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 19 establishes a therapy against inflammation aimed at disarming free No less important is eliminating bacteria such as Propiobacter acne. The Purifying Cream contains Triclosan and Different varieties of acne can be a natural antiseptic product, tea tree oil.
treated with Easy TCA Tea tree oil kills bacteria in the sebaceous follicle, but with fewer side Some acne types cannot be treated Apply the Basic Protocol, according to effects than benzoyl peroxide, and none the specific type of acne.
with cosmetic procedures alone; they of the drawbacks of antibiotics.
require a dermatological approach.
1) Acne comedones Do not apply Easy TCA peeling for 2) Microcystic acne tuberose, rosacea, conglobata, or 3) Acne cosmetica necrotic acne, nor in cases where To unclog pores, the Purifying Cream 4) Papulo pustular acne lesions the acne problem is related with an contains glycolic acid, an alpha-hydroxy 5) Barbae foliculitis acid that enhances the drainage of the 6) Acne pigmentary sequels follicular opening.
7) Acne scars (see Abrasive Protocols) Stopping Inflammation With cyclodextrin-encapsulated pure triclosan, glycyrrhetinic acid and vitamin E, the Purifying Cream 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 20 Easy TCA Acne Protocols Acne Comedons Protocol Microcystic Acne and Milium (Whiteheads) Applying Easy TCA Even when not of an acneic nature, whiteheads can be treated just like Do the Basic Protocol until frosting points appear. Apply the Post-Peel Mask and leave on until the next morning.
After the peeling procedure, clean the skin with Skin Tech Pre-Peel Cleanser.
After the peeling procedure, clean the Apply the Purifying Cream once or twice skin with Skin Tech Pre-Peel Cleanser.
a day, depending on the skin’s condition.
Apply the Purifying Cream once or twice In week 4 (or 5), clean the cystic lesions a day, depending on the skin’s condition.
and apply Easy TCA peeling solution In week 4 (or 5) eliminate the Eliminate the comedones before the comedones and apply Easy TCA peeling Open the cystic lesions and clean them peeling procedure, using the appropriate solution locally.
before the peeling procedure. Use a number 11 scalpel or the edge of a Physicians should investigate the sterilised needle.
possibility that the acne is caused by the use of cosmetics.
Applying Easy TCA Applying Easy TCA Do the Basic Protocol until frosting points appear. Apply the Post-Peel Mask.
Do the Basic Protocol until frosting points appear. Apply the Post-Peel Mask.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 21 Easy TCA Acne Protocols Acne Papulo-pustulosa - If the skin has improved noticeably Daily Care Between Peelings Apply Easy TCA according to the Basic Begin applying the Purifying Cream the morning after the first peeling procedure.
- If there is just a slight improvement Apply on the whole area. Continue using Prescribe an antibiotic treatment (such the Purifying Cream during the peeling as minociclyne). Apply Easy TCA procedures and afterwards. Prescribe according to the Basic Protocol.
antibiotics when required.
Results: One Easy TCA session Results: Four Easy TCA Daily Care After Peelings Acne Papulo-pustulosa can be treated sessions + Purifying Cream with Skin Tech Easy TCA, but not with For at least six weeks after the four any other TCA peelings.
peeling sessions, clean the skin using Skin Tech Pre-Peel Cleanser. Apply the Purifying Cream once or twice a day, depending on the skin’s condition. On week 4 (or 5), clean the lesions and Two weeks before the first Easy TCA apply the Easy TCA peeling solution peeling session, prescribe the Purifying Cream, to be applied twice a day, morning and night. After two weeks, evaluate the skin’s condition and determine the following treatment.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 22 Easy TCA Acne Protocols Foliculitis Barbae Prescribe the use of vinegar alcohol as an after-shave lotion. Apply Purifying Cream after cleansing.
Acne Pigmentary Sequelae Acne pigmentary sequelae can be treated easily: perform 4 Easy TCA procedures, one per week, to obtain Foliculitis points can be opened and cleansed using a number 11 scalpel or The following day, begin applying the a sterilised needle.
Blending Bleaching Cream.
Apply Blending Bleaching twice a day: Applying Easy TCA in the morning on the whole area, and in the evening only on the pigmented Do the Basic Protocol until frosting points Acne Pigmentary sequela 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 23 Easy TCA Protocol for Hands, Forearms and Arms Hands: Easy TCA for Skin Regeneration Apply three coats of Easy TCA, one after the other, without aiming to achieve frosting. Let each coat dry completely before applying the next coat. If areas of frosting appear, do not apply any further coats. Treat pain by cooling the Daily Post-peeling Care treated area with a 3M Cold Pack.
Patients under 40-45: Apply Vit. E Anti- oxydant in the morning, and Re-Nutriv ACE Lipoic Complex in the evening.
Patients over 40-45: Apply DHEA When the last coat of solution has dried, PHYTO in the morning, and Re-Nutriv apply the Post-Peel Mask in the ACE Lipoic Complex in the evening.
quantities indicated on the dispensing card. Leave the Post-Peel Mask on until the following morning.
If any pain is felt: cool the treated area with a 3M Cold Pack Desquamation usually takes place after at least one week, and lasts four or five Remove all jewellery before applying days. Repeat the treatment four times, the Easy TCA peeling solution.
at two-week intervals, except when desquamation has not stopped.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 24 Easy TCA Protocol for Hands, Forearms and Arms Easy TCA for Treatment of Localised Blemishes or Hyperkeratosis (Lentigos) on Hands and Forearms Easy TCA Peel + Only Touch while ensuring a more even regeneration Using a cotton bud or wooden toothpick, of tissue. Repeat if necessary, following apply Only Touch carefully and precisely the OnlyTouch Protocol. Follow daily on the blemish or keratosis.
care between and after peelings.
Considerable frosting will appear (see Post-Peel Caution Inform patients that the crusts produced How fast the frosting appears will depend by Only Touch treatment are brown on the thickness of the keratosis.
(dark). They last for about 12 days and Patience is required (follow the Only leave an erythema; this does improve, Touch specifications). Even out the but can take three weeks to three treatment by applying Easy TCA in months to disappear. Patients must accordance with the Basic Protocol over refrain from scratching these areas, as the treated area as a whole. Do not this could result in permanent scarring.
hesitate to apply the Easy TCA solution Patients must wear total sun block and on small areas that have just been avoid intense light. Preventive or curative treated with Only Touch. Using Easy measures must be taken in cases of TCA in the regeneration cycle following persistent erythema or pigmentary Frosting: considerable frosting will appear OnlyTouch reduces the risk of pigmentary rebounds than can result from using OnlyTouch on its own, 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 25 Easy TCA for Treatment of Localised Blemishes or Hyperkeratosis (Lentigos) on Hands and Forearms Treatment of hyperkeratosis and lentigos as signs of photoageing.
Predominance of Lentigos: Combine an Antioxidant and an Anti-Tyrosinase Predominance of Hyperkeratosis Use the Anti-Ageing Daily Care Protocol Patients under 40-45: Apply the Blending Bleaching Cream in the morning, and Patients under 40-45: Apply Vit. E Anti- Re-Nutriv ACE Lipoic Complex in the oxydant in the morning, and Re-Nutriv Skin treated with Easy TCA + Only Touch, after 15 days Normal crust after Easy TCA treatment (Day 8) ACE Lipoic Complex in the evening.
Patients over 40-45: Apply DHEA Patients over 40-45: Apply DHEA PHYTO in the morning, and Blending PHYTO in the morning, and Re-Nutriv Bleaching Cream in the evening.
ACE Lipoic Complex in the evening.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 26 Easy TCA for Treatment of the Neck and Décolleté Neck and/or Décolleté Showing Little Damage _ Gentle TreatmentThe décolleté area is generally treated Apply the Post-Peel Mask to the areas A cloudy pinkish frosting on the skin will at the same time as the neck and face.
treated, starting from the first spots of Proceed as follows: Apply the Post-Peel Mask, and then go Follow the Easy TCA Basic Protocol.
Use the appropriate daily care creams.
on to treat the face in accordance with Very Damaged Décolleté On the face, repeat four times at eight- the desired protocol.
Apply the Easy TCA solution to the day intervals. On the neck and décolleté, Apply the abrasive protocol in cases of décolleté area and leave to dry.
repeat at 15 days intervals (due to longer In some cases it is better to apply extensive photoaged areas.
Unideep on the decollete to obtain a Apply the Easy TCA solution to the neck uniform white pinkish frosting.
In the case of localized lentigos, combine and leave to dry.
Neck and/or Décolleté Easy TCA and Only Touch.
Apply Easy TCA basic protocol on the Move on to the face.
Showing Moderate Damage face and neck to obtain frosting ponits.
Repeat the Easy TCA basic protocol Look for the first spots of frosting on the Moderately Aggressive Treatment With 3 – 4 weeks interval for décolleté Apply several coats of Easy TCA solution With one week interval, on the face.
Let each coat of solution dry before successively to the décolleté area and applying the next coat.
then the neck.
Repeat the peelings at two- to three-week intervals, depending When spots of frosting begin to appear Let each coat dry before applying the on the skin’s condition.
on the face, stop applying the solution to the neck and décolleté area.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 27 Easy TCA Protocol for Treatment of the Body and Legs The Easy TCA solution and Post-Peel Mask can be applied over extensive From the first day after the peeling surface areas, to treat various problems procedure apply the prescribed Skin such as discoloration and photoageing.
(To treat scares, see abrasive protocols) Hyperchromia : Blending Bleaching Cream, twice a day.
Photoageing : DHEA PHYTO, in the Degrease the skin For the treatment of certain problems.
morning, and Re-Nutriv ACE Lipoic It may be necessary to perform a light Complex in the evening.
abrasion before applying Easy TCA.
Applying Easy TCA (See abrasive protocols, and apply the Dry skin : Vit. E Anti-oxydant at least “pilar keratosis” procedure).
two times a day.
For minor cases – follow the Easy TCA Basic Protocol. Repeat four (five) times Flaccid skin : Actilift with DMAE, and at two weeks intervals.
Re-Nutriv ACE Lipoic complex.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 28 Easy TCA Abrasive Protocols The Easy TCA sand abrasion kit This type of sand abrasion (abrasion with sandpaper) Preparing the Abrasion Procedure renders the skin permeable by removing the stratum Roll a sheet of sandpaper around a rounded object (see photo).
1) 10 sheets of single-use sandpaper After sand abrasion, the course of action sterilised by gamma rays (220 grain).
will depend on the protocol chosen: 2) Bismuth subgalate: healing and 1) Apply the Post-Peel Mask directly, Kit for Combined Abrasion with Easy TCA disinfectant powder. Presented in a 30g followed by occlusion (treatment of the jar for medical use and two small Certain problems , like striae and scares, due to their deep cutaneous origin, can envelopes to be used by the patient, as not be solved with peelings, (not even part of the post-peel daily care after the 2) Topical anaesthesia can be with the deepest ones).
abrasion procedure.
administered followed by the Easy TCA The abrasive Easy TCA protocols can solve these problems, without using Peel solution and then, optionally, more peeling solution. This means Using the Sandpaper Combined occlusion (treatment of striae). Also getting good results without problems.
without occlusion.
Disinfect the skin with alcohol.
Stretch the skin with one hand and rub Degrease with acetone.
gently and carefully back and forth with the sandpaper.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 29 How to choose the right depth Grade 0 Sand Abrasion Grade II Sand Abrasion Grade III Sand Abrasion: The Desired Level: Subjectively: The patient feels nothing.
Objectively: Epidermal palpation The patient perceives the abrasion as The patient feels the first pain from the conveys a sensation of corneal palpation unpleasantly painful. Proceed with abrasion; the abrasion must usually be – that is, the finger slides over the caution: the abrasion has reached the stopped at this point, although the pain surface layers of dehydrated papillary dermis.
threshold does vary from one patient to corneocytes. If sand abrasion is limited another (hence the importance of to this level, the anaesthesia will be of poor quality and the peeling too The first drops of blood appear. The superficial, and thus insufficient.
abrasion must be stopped at this point.
The appearance of the very first drops Epidermal palpation gives a sensation Grade I Sand Abrasion of blood indicates Grade III Superficial.
of keratinocyte palpation: the finger feels a breaking sensation as it passes over Grade III Medium and Deep correspond The patient notices the abrasion, but the living, well-hydrated keratinocytes to the appearance of many points of Physicians can reach different depths with the experiences no pain.
revealed by the abrasion, when bleeding followed by more extensive sand abrasion technique compared with the dehydrated and bleeding, and distinct entry.
slippery corneocytes of the adjacent, Positive Keratinocyte Palpation Epidermal palpation usually conveys a non-abraded skin. Apply the peeling sensation of “corneal” palpation. If sand solution and the Post-Peel Mask, or the The finger slides over the dehydrated abrasion is limited to this level, the Post-Peel Mask only, according to the corneocytes of the non-abraded skin anaesthesia will be insufficient and the chosen protocol; then occlude if the and is halted on the well-hydrated chosen protocol so suggests.
keratinocytes revealed by the abrasion.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 30 Easy TCA Abrasive Protocols How to choose the right depth Easy TCA Striae Treatment into the papillary or even the reticular Using Bismuth Subgalate The peeling must be performed by experienced physicians only.
With Grade III Superficial, the Before the Easy TCA anaesthesia will be rapidly effective and The bismuth subgalate facilitates the Physicians must monitor patient the peeling deeper. Take care with the post-peel and prevents patients from progress carefully. Strict observation is amounts of acids! having to perform complex local care.
Sprinkle the powder on the moist, de- - Disinfect with alcohol.
Other abrasion techniques can be used.
epidermised areas. Spread using a Preparation Before the Peeling - Leave to dry.
This techniques are not to be performed cotton bud or finger. Re-apply powder - Degrease with acetone.
by beginners. Just for experienced on the moist areas over the first two physicians. Micro dermoabrasion : days. Patients must refrain from - Divide the area to be treated into perform an uniform abrasion, with scratching the area. Protect the treated Two weeks before the procedure, sub-areas of 10 cm x 10 cm. to coridon grains, Perform a zones with a dressing that does not prescribe the use of Blending Bleaching recognize the first treated areas.
microscopically uniform abrasion. Clean adhere to the wounds (e.g. Melolin by Cream twice a day.
the coridon grains. Also Erbium laser Smith & Nephew). Around the fourth can be used for the abrasion procedure.
day, apply Vaseline to assist Prescribe a Painkiller The abrasion should be done on the desquamation and prevent pruritus.
Patients should take codeine + regions of normal skin, between the Follow with the prescribed daily care paracetamol before and after the striae atrophic striae. Stop the procedure when cream. For a deep moisturizing effect, procedure. The same painkiller should small drops of blood are visible. The apply Vit. E Anti-oxydant, twice a day be taken one hour before the procedure peeling solution and the Post Peel Mask and two hours after the procedure.
stimulate the atrophic areas, while the abrasion procedure causes a 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 31 Easy TCA Striae Treatment Abrasion with Sandpaper Wear gloves while working.
Roll up the sandpaper around a plastic The sand abrasion procedure is not Carry out painless, slow, gentle and painful at all. However, applying a uniform sand abrasion on the whole peeling solution on a previously area. Perform grade II abrasion.
exfoliated area could be painful, so anaesthesia is required. Anaesthetise Grade II abrasion by applying gauze soaked in 2% lidocaine with adrenaline (about 5 cc per 10 x 10 cm area). Leave it on for The sandpaper provides a more uniform about 10-15 minutes under plastic film.
abrasión than the coridon grains or the Vasoconstriction will take place when laser Erbium, but coridon grains and the anaesthesia begins to work.
laser Erbium can replace the sand paper for this purpose.
Carry out the sand abrasión just until the very first points of blood (tiny
ones) show up. Stop sand abrasion at this moment.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 32 Easy TCA Abrasive Protocols Easy TCA Striae Treatment Applying Easy TCA Applying the Post-Peel Mask Choosing the Right Apply the Easy TCA peeling solution as Apply about 0.5 g of Post-Peel Mask follows: Apply one vertical coat and then per 10 x 10 cm surface area, under The depth of the peeling one horizontal coat. The application of occlusion. Let the Post-Peel Mask work procedure will depend on different the Easy TCA peeling solution does not between 6 and 24 hours. The Post-Peel factors: 1) the abrasion depth; produce pain or discomfort, except in Mask under occlusion will cause 2) the number of Easy TCA coats of the surrounding areas where there is significant inflammation at the bottom peeling solution; 3) the occlusion period.
not enough anaesthesia working.
of the atrophic striae. This stimulates A light-pinkish frosting is generally cellular division and increases the obtained quickly. It appears on the number of dermic cells. Physicians Fotografía del Dr. M. Adato normal (not atrophic) skin between the should remember that the peeling The peeling procedure gets deeper striae. The combination of the Easy TCA procedure gets deeper when the depending on the abrasion depth. A peeling and the abrasion procedure occlusion takes longer: a longer deeper abrasion means a deeper gives rise to a resurfacing effect on the occlusion means a deeper peeling.
peeling procedure. Be conservative: normal skin between the striae. This start with a superficial treatment.
stimulates the growth of normal When in doubt, choose a superficial 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 33 2) Number of Easy TCA Peeling If necessary, steadily increase the depth Epidermal Liquefaction After 24 of the treatment (more occlusion time).
Hours of Occlusion Look at the frosting. For superficial striae Remove the plastic after a period of 6 with few atrophic striae, the frosting Should epidermal liquefaction occur, to 24 hours.
should be a whitish-pink colour. For dust the area with bismuth subgalate, deep and atrophic striae, the frosting continuing as long as the skin remains Duration of Occlusion should appear only on the normal skin moist. Cover with a dressing that will between the striae; it must be pinkish – not adhere to the wounds (e.g. Melolin never pure white.
6-hour occlusion: superficial treatment by Smith & Nephew) so as to prevent the dressing from sticking to the skin.
For patients with thin skin, apply just the Post-Peel Mask and occlusion 12-hour occlusion: medium-depth When the skin and the powder have directly, as in the Décolleté Protocol dried, wait 24 hours before applying (Abrasion + Post-Peel Mask +
Vaseline (petrolatum), used to assist 24-hour occlusion: deep treatment desquamation and prevent pruritus.
From day 4- 5 to day 7, Vaseline should Never apply a deep treatment on the be applied to assist desquamation.
Occlude using an impermeable plastic breasts or the upper thighs.
If necessary, steadily increase the depth of the treatment (more occlusion time).
Always start with a six hours of occlusion, for example, in order to test the patient’s skin reaction.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 34 Easy TCA Abrasive Protocols Easy TCA Striae TreatmentIn the case of atrophic and long striae, Physicians must monitor patient there is significant inflammation. When progress carefully. Strict observation is this type of striae are treated with Easy TCA, the following occurs:1) Easy TCA + sand abrasion Pigmentary Rebound Prevention Causes significant stimulation of the Before and After the Peeling normal keratinocytes, which increase in number. This gives skin a smoother look, Always administer preventive treatment making it more even and softer to the for any hyperchromic side- effects that could arise. Apply the 2) Post-Peel Mask under Blending Bleaching Cream twice a day, Treated area with bismuth subgalate two weeks before the peeling procedure.
Continue with the Blending Bleaching Causes strong dermic stimulation. This Cream for at least six weeks after the makes flaccid skin look fresher and peeling procedure. Apply the Blending improves its tonicity.
Bleaching Cream twice a day. Avoid exposure to the sun.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 35 Complications usually increase with the depth of the peeling.
Moisturiser and Skin Protection Avoid infection and prolonged erythema.
If longer than 15 – 21 days, prescribe Always start with a superficial protocol Patients under 40-45: Apply Vit. E Anti- a topic corticoid.
and then gradually work deeper.
oxydant in the morning, and Re-Nutriv ACE Lipoic Complex in the evening.
Prescribe a painkiller to ease pain on The deeper the peeling, the more expert the first day.
and careful the physician must be.
Patients over 40-45: Apply DHEA PHYTO in the morning, and Re-Nutriv Avoid contact with water for several Patients must always be informed of ACE Lipoic Complex in the evening.
days (it could cause pain and infection).
the type of post-peeling treatment they Administer antibiotics if necessary.
will undergo.
Patients should use the prescribed daily care products.
Avoid sunlight during the three months Do not treat patients with “cutis laxa” Be cautious of the Koebner phenomenon (Psoriasis, Vitiligo).
Frequency of Treatment and Number of Sessions .Striae type.Number of sessions
Once a month .Small superficial striae.2-3 sessions
Once a month .Atrophic, old, wide, deep striae.4-10 sessions
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 36 Easy TCA Abrasive Protocols Protocols for Acne Scarring Protocols 1 to 3, progressively -Always start with a superficial protocol and then gradually work deeper.
1) Combined Abrasion + Easy TCA -Do not use mechanical abrasion on infected skin.
A light abrasion with sandpaper + topical Topic anaesthesia -Prescribe antibiotics where required.
anaesthesia + a coat of Easy TCA -Avoid sunlight during the three months solution + Post-Peel Mask _ a cloudy frosting will generally appear.
-Pigmentation-resurgence treatment is always advisable.
2) Combined Abrasion + Post-Peel Mask -Strict monitoring and prescription of a painkiller are necessary in cases of (follow the “Décolleté” Protocol) abrasion or occlusion.
-In cases of abrasion before the acid, 3) Combined Abrasion + Easy TCA + always administer a topical anaesthesia Post-Peel Mask + Occlusion by applying pads of 2% lidocaine with Note that the Easy TCA peeling solution adrenaline under plastic film (for 10- is not used.
15 minutes).
-Avoid all contact with water (baths or showers) in the days following an abrasion.
after five sessions, one session a week.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 37 Treatment of very Damaged (Photoageing) Décolleté For Photoageing Associated with Following sand abrasion, apply the Post- Peel Mask. Note that no Easy TCA Numerous Lentigo Lesions: peeling solution should be applied.
Apply Only Touch combined with the Easy TCA Basic Protocol For Photoageing Associated with Cover the treated area with an impermeable plastic film (photo) and Extensive Hyperchromia: leave it on for 12 to 24 hours, depending on the depth to be reached.
Combine Sand Abrasion + Post-Peel Post Peel Mask under Once this time has elapsed, remove the Mask (not Peeling Solution) + Occlusion.
occlusion (12-24 hours) plastic film (photo).
Disinfect the skin.
Perform gentle abrasion with sandpaper.
Abrasion Depth: Type II Abrasion Stop the abrasion just before or when the first spots of bleeding appear, and when there is positive keratinocyte palpation. In expert hands, the intraepidermal Erbium laser can be used instead of sandpaper.
Local edema and erythema, two days after the peeling.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 38 Easy TCA Abrasive Protocols Treatment of very Damaged (Photoageing) Décolleté Daily Care During Desquamation Patients should avoid exposure to the Erythema will be clearly noticeable, sun throughout the entire treatment and along with local edema.
during the months following it.
Dust the treated zones with bismuth Avoid contact with water. Avoid getting the treated region wet during the first Cover with a dressing that will not adhere days after the peeling procedure.
to the wound (e.g. Melolin by Smith & Patients themselves should apply Prescribe a moderate painkiller, and subgalate for as long as the skin remains perhaps an antibiotic as well if there is damp (24-48 hours maximum).
acne on the treated areas.
Treated areas day 4-5 after the peeling. Few hours before desquamation Apply Vaseline for a few days, when the skin has dried. This will assist There may be quite considerable Treated area with bismuth subgalate 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 39 From around the fifth day onwards, Patients should use the prescribed daily generously apply Vit. E Anti-oxyidant care products.
according to the physician’s instructions.
Moisturiser and Skin Protection Always administer preventive treatment Repeat the treatment every 3-4 weeks, for any hyperchromic side-effects that Patients under 40-45: Apply Vit. E Anti- depending on the skin’s condition.
could arise. Apply the Blending oxydant in the morning, and Re-Nutriv Bleaching Cream twice a day, two ACE Lipoic Complex in the evening.
It is very important that the prescribed weeks before the peeling procedure.
daily care products be used.
Continue with the Blending Bleaching Patients over 40-45: Apply DHEA Cream for at least six weeks after the PHYTO in the morning, and Re-Nutriv Post-Peel and Inter-Peel Follow- peeling procedure. As soon as possible ACE Lipoic Complex in the evening.
once the desquamation is over, apply the Blending Bleaching twice a day.
Follow daily care. Avoid exposure to the Physicians must monitor patient Avoid exposure to the sun.
sun throughout the entire treatment and progress carefully. Strict observation is during the months following it.
Pigmentary Rebound Prevention Before and After the Peeling Procedure 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 40 Easy TCA Abrasive Protocols Easy TCA Arms Protocol to Treat Keratosis Pilaris Easy TCA in Combination with Other Treatments Keratosis pilaris often appears on the Following the abrasion, apply topical Easy TCA is a stimulant treatment rather arms and makes the skin rough to the anaesthesia as in the Easy TCA Striae than an aggressive chemical peel. It can be safely combined with different cosmetic procedures during the same Then use Easy TCA Basic Protocol _ session. Easy TCA can be combined Patients under 40-45: Apply Many spots or some “clouds” of frosting with a filling, a telangiestasia coagulation, Vit. E Anti-oxidant in the morning, and will appear.
a botulinic toxin injection, a lentigo Re-Nutriv ACE Lipoic Complex in the treatment with Only Touch, or a Apply the Post-Peel Mask and leave it resurfacing chemical procedure on the on until the following morning.
upper lip (with Lip & Eyelid Formula).
Patients over 40-45: Apply DHEA Thus many different procedures may PHYTO in the morning, and Re-Nutriv Repeat the procedure four or five times be performed within a single session ACE Lipoic Complex in the evening.
at two-week intervals.
and without prior preparation of the skin.
Maintain the results by repeating the Easy TCA + Slimming Diet peelings or by performing surface abrasions from time to time.
Improves tired appearance of the skin.
Skin Preparation (Grade I) The implementation of a skin regeneration cycle from the start of a Disinfect the area.
slimming diet limits the classic loss of tone in the face. Apply the Easy TCA Perform a light abrasion (Grade I) with Basic Protocol and repeat 4 times, one session a week.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 41 Easy TCA in Combination with Other Treatments Easy TCA + Epilation - Easy TCA + Coagulation of Telangiectasias application is sufficient, following the Easy TCA to Avoid Pigmentary Basic Protocol and immediately after the treatment.
Easy TCA Combined with a Deep Easy TCA can be used for ensuring an even result of a deep peel, when applied to the untreated adjacent zones. For Frosting in Lip & Eyelid example, Lips & Eyelid, a deep peeling Using Easy TCA immediately after of the eyelids or of the upper lip, can be after a phenol treatment manual, electric or high-frequency performed with phenol, along with an (Before Easy TCA + Blending Bleachin Cream) epilation, the scarring phase can be Easy TCA for the rest of the face in the With this combination, pigmentary bypassed or shortened.
same session.
Results after three months rebounds owing to medium-depth or very deep peelings can generally be It is also suitable after coagulation of avoided or treated. Repeat the Basic telangiectasias. A single application Do 4 Easy TCA sessions, one per week.
Protocol four times when the skin’s according to the Basic Protocol There are cases where Lips & Eyelid condition permits. Easy TCA can be immediately after the treatment is can be better combined with Unideep used to treat pigmentary rebound sufficient. There is a lower risk of post- (medium, papillar dermis peel) for the associated with other peeling therapeutic secondary infections. The procedures, or to attenuate crusts or scabs last less than half the visibledemarcation lines after a deep time. A single, highly localised 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 42 in Combination with Other Treatments Easy TCA as Pre-Peel The botulinum toxin is intramuscularly Easy TCA + Filling administered, while the peeling just penetrates the skin. The targets are The Easy TCA Basic Protocol may be Apply Easy TCA Basic Protocol eight different. Since the toxin produces a applied immediately after wrinkle filling.
days before applying a medium or deep local paralysis, the skin is able to peel, just to obtain frosting points.
regenerate without movement. Collagen Easy TCA + Lasers and elastin fibres probably adopt a more Easy TCA + Botulinum Toxin uniform arrangement. Easy TCA Post- The combination of Erbium or CO2 Peel Mask provides numerous lasers with the Easy TCA Basic Protocol, antioxidants, ready to fight free radicals.
Botulinum toxin used in association with or just the Post-Peel Mask applied after As a result, vasodilatation lasts a shorter this peel achieves excellent results.
the treatment session, reduces erythema Ideally, the injection should be time and/or the risk of pigmentary administered at least 5 minutes before applying the Easy TCA Basic Protocol (frosting points). This combination improves both treatments.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 43 Advantages of Easy TCA No Risk of Toxicity With Easy TCA, the Post-Peel Mask is Instructions for Safe Use: No Special Skin Preparation formulated to solve this problem in two Easy TCA can be safely applied. There ways. The Post-Peel Mask attenuates If physicians follow the instructions for is no need to prevent a toxic reaction the effect of the peeling solution, without use, there are no contraindications. Easy The first Easy TCA peeling of the four from a biological source. As explained the need for a neutralising agent; TCA can be used on all skin types, in sessions could be considered equivalent above, the Easy TCA exfoliant mixture meanwhile, it also brings to the skin any season of the year.
to the skin preparation used in other includes 15% m/m TCA, ascorbic acid, vitamins and ingredients that fight free It can be safely used to treat the face peeling procedures. Only in the case of citric acid, saponins and excipients.
radicals. These fight and neutralise free as well as the rest of the body. There is oily and thick skin is it necessary to Post-Peel Mask includes a number of radicals at the right time and where they no problem as regards the frosting: even clean and degrease the skin, a normal vitamins, trace elements, growth factors, have been produced. Vitamins stimulate if the peeling solution is unevenly part of other peeling procedures.
lipids and antioxidants.
cutaneous metabolism and skin applied, the resulting desquamation is regeneration. Trace elements and lipids normally even. Side-effects are rare, Generally, a chemical peeling is also participate in skin restructuring after and when they do occur (in lesions automatically associated with an the peeling procedure. Thanks to these associated with scratching, for example), inflammatory process, which gives rise combined effects, one Easy TCA peeling they are generally temporary.
to free radicals, able to promote and can be done per week.
sustain inflammation: Peeling procedures = Inflammatory Process = Liberation of Free Radicals = Skin Damage = Slow Healing = Slow 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 44 Advantages of Easy TCA Easy TCA Application – Just Two Four Easy TCA sessions must be done.
Materials are provided almost ready to Some physicians do five or six sessions use. They are practical enough to lower per cycle, but this is not a rule (it is not the risk of technical errors.
Moisten two cotton swabs with Easy effective for all skin types). There should TCA solution. Gradually apply as many be at least five days between peeling Gentle Treatment: coats of peeling solution as needed for sessions, and no longer than two weeks.
the first spots of frosting to appear. Leave If fewer than five days pass between There is no need of sedation or each coat to dry before applying the two sessions, there is a risk of side- anaesthesia. When Post-Peel Mask is next coat. Apply the Post-Peel Mask effects. If more than two weeks pass applied the slight sense of burning skin There is no dark desquamation such as when the first frosting spots appear.
between peeling sessions, the peeling that produced by medium or deep Massage to help the Post-Peel Mask could be less effective, with less dermic procedures. Patients leave the doctor’s penetrate the skin. According to the For Patient Convenience: surgery with no visible marks. The Easy TCA Basic Protocol, the peeling erythema does not last longer than half session ends when the Post-Peel Mask an hour. Even makeup can be used Easy TCA produces a very light has been applied.
after the peeling procedure.
desquamation. On the third or fourth It only takes eight to ten minutes to do day after the peeling, patients look as a full Easy TCA peeling on the face and if they had been exposed to the sun for neck. No time is wasted with Easy TCA.
a prolonged period. The use of daily care products and a few intelligent measures help to reduce the peeling Skin Tech packages its products in the effects, which are not comparable to most convenient way.
the effects produced by other peeling 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 45 How Easy TCA Works Many Possible Indications: Easy TCA Really Works: TCA is a proteolytic, non-toxic, to foster the regeneration process.
hydrosoluble molecule that self- Exfoliation deeply modifies the post- It can be used to reduce signs of ageing, The efficiency and results of the four neutralises through the combination and peel permeability of the skin and allows wrinkles, hyperchromia, acne and solar (five) Easy TCA sessions are lysis (destruction) of skin proteins. The for quick, deep epidermal and dermal keratosis. It can be combined with many comparable to the results of a 30% TCA, Easy TCA peeling solution coagulates penetration of the active ingredients in but with none of its disadvantages. Easy skin proteins. Depth depends on the the Post-Peel Mask. The Post-Peel TCA does not change patients’ number of coats of peeling solution.
Mask is not a neutraliser; it is a cream Daily Care Products: appearance and does not involve the Depth may be determined according to with stimulating, antioxidant and healing risks associated with deeper peelings.
the frosting type (see previous properties – all in one product.
Skin Tech daily care products have been instructions for use). Cutaneous cells specially designed for the needs of skin destruction triggers a chain of reactions: that has recently undergone a peeling keratinocyte destruction induces and The Post-Peel Mask seeks out the free procedure. Different types of products stimulates skin regeneration. The radicals produced during the normal are available: for flaccid skin, for ageing regeneration process comes from the post-peel period. It provides the vitamins, skin, and for acne-prone skin.
basal layer or from the reservoir of trace elements and fatty acids required keratinocytes in the pilo sebaceous units.
for quick skin regeneration. The Post- This results in deeply cleansed skin.
Peel Mask disinfects the skin and promotes quick skin regeneration, Other commercial exfoliation treatments allowing one peel to be performed every eliminate epidermal cell layers and then week. It fights post inflammatory rely on the spontaneous regeneration hyperpigmentation, thanks to its process, with no active therapeutic antioxidants and antityrosinase effects.
intervention. Easy TCA, with the Post- Post-peel hyperpigmentation rebounds Peel Mask, adds prolonged stimulation are very uncommon after using the Easy 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 46 Advantages of Easy TCA Active Ingredients TCA Basic Protocol.
Trichloroacetic Acid (TCA) as the skin. Vitamin C stimulates that form distinctive foamy, soapy collagen synthesis and promotes skin solutions when combined with water.
The repetition of the Basic Protocol of Trichloroacetic acid is not a component Like other glycosides, saponins provide Easy TCA (until frosting points appears) of the base solution. Adding the right the skin with their water binding four or five times creates a progressive amount of TCA to the base solution (see properties. They improve acid and long-lasting stimulating effect. It product instructions on the box) Citric acid is an alpha-hydroxy acid. It penetration and bring evenness to the stimulates the fibroblasts to produce transforms it into an adjuvated and enhances peeling trichloroacetic acid peeling treatment. Saponins can more collagen, elastin and GAGs in the stabilised Easy TCA solution.
skin penetration, functioning as a chelatin contribute to the post-peel healing dermis. To reach a local deeper level, agent and protecting the solution and process as well, and there is some combine Easy TCA with other protocols the skin from free radicals. It is also an evidence that saponins also have such as sand abrasion, or other Skin acidifying and buffering agent.
antimicrobial benefit. Saponins foster Tech peels such as Unideep, Only Touch the healing process.
or Lip & Eyelid Formula.
Protects the skin and improves saponin The comprehensive action of the peeling solution + Post-Peel Mask is a complete and progressive renewing of the skin.
Sodium Laureth Sulfate It is more stimulating than destructive Easy TCA Base Solution Surface active, emulsifying and wetting peeling, and allows for a normal social agent that degreases and emulsifies oils life during treatment.
L-Ascorbic Acid (Vitamin C) and fats and suspends dirt.
As a component of the base solution, L-ascorbic acid improves trichloroacetic Saponins and Excipients acid (TCA) penetration. It also fights free Saponins are an extensive and varied radicals and protects the solution as well group of glycoside plant constituents 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 47 Urea: Keratolytic, used to treat dry skin; Skin Tech uses Magnesium Ascorbyl it increases skin permeability.
Phosphate (MAP), which is the most This is an antioxidant and antityrosinase.
stable ascorbic acid and hydrophilic It helps in treating hyperpigmentations Silicium (Methylsilanol Manuronate): derivative. It is quickly transformed into and avoiding post-peel inflammation This oligo element is strongly linked to Vitamin C on and inside the skin by proteoglycans and phospatase, an abundant enzyme.
mucopolysaccharides, hyaluronic acid The Post-Peel Mask has an antioxidant and chondroitin sulfate. Silicium plays Magnesium Ascorbyl Phosphate is better Pure cyclodextrin microencapsulated effect, stimulates skin regeneration, and an important role in skin healing and is than ascorbyl palmitate (AP), used in retinol is used in this cream.
promotes healing. Its action is very necessary to fight signs of ageing.
other preparations, because the important for a safer papillary dermis esterification of MAP occurs on the peel. The post-peel penetration of carbon where the "enediol" function is A trace element that accelerates skin ingredients is dramatically modified when Vitamin C is a potent antioxidant. It found (2nd carbon). This enediol is healing; its penetration is clearly the peeling solution is applied works in water solutions, where it responsible for the acidic and antioxidant enhanced when combined with beforehand. The post-peel rate of captures free radicals; with this action, properties of the molecule. This is why methionin. Creams based on selenium penetration is much higher than the Vitamin C prevents protein destruction.
the esterification of this function protects methionine enhance healing after laser normal skin rate. The skin is much more It also exerts a protecting role over other MAP and allows for longer and better resurfacing treatment or peeling, and permeable during the close post-peel cellular antioxidants. This action is antioxidant efficiency. The enediol prevent seborrheic dermatitis. Selenium period: sebum and corneocytes no particularly valuable when there is an function on carbon 2 of ascorbyle is a component of Glutathion Peroxidase longer act as a barrier and hydrosoluble increased number of free radicals, which palmitate is not protected by (GPX) [family of antioxidant enzymes] ingredients can rapidly pass through occurs with wounds (whether they are which breaks down peroxides. It reduces this modified epidermis, so that high infected or not) and in exfoliated areas hydroperoxides and acts as an quantities of stimulating factors and after a peeling treatment.
This is an alpha hydroxy acid. It is an intermediary on the cyclo-oxygenase antioxidants can reach the dermis antioxidant with buffering and chelating and lipo-oxygenase pathway, reducing 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 48 Advantages of Easy TCA inflammation. It prevents the production penetration of other active ingredients of inflammatory and immunosuppressive of the Post-Peel Mask.
cytokines, and boosts both cellular and humoral immunity. Combination with Vitamin E strengthens its protective Antibacterial. This has been used for action and creates a tretinoin-like effect.
the disinfection of wounds and burns.
Vitamin E (Tocopheryl Acetate) This Base solution and Post-Peel Mask for Vitamin H (Biotin – Coenzyme R – most stable ester of Vitamin E is 24 peelings.
automatically hydrolyzed into pure The metabolic action of the biotin is Vitamin E after cutaneous absorption.
carried out by biotin-dependent The acetate form is very interesting enzymes, which act in the synthesis of Base solution and Post-Peel Mask for because it constitutes a reservoir that the purines. It is a stable, water- and slowly releases Vitamin E into the skin.
alcohol-soluble monocarboxylic acid, Vitamin E traps the oxygen free radicals which acts as a co-enzyme or also as Set for Stretch Marks: that can cause damage to the tissues.
a "growth factor", even in very small Sterilised gamma rays, wet or dry Vitamin E blocks oxidative chain quantities. Deficits of biotin are sandpaper and bismuth subgallate reactions, inhibiting the formation of characterised by exfoliative dermatitis lipoperoxyls in the cell, and protects and hyperkeratosis with alopecia. Topical nucleic acids and proteins.
application of biotin lessens the secretion A disinfectant, moisturiser, and stabiliser for vitamins, propylene glycol diminishes corneocyte cohesion. This promotes the 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 49 TCA + AHA + Antioxidants Directions for Use solution), extract 0.2 to 0.5 cc. of the Only Touch is a local deep peeling Skin Preparation before Only Touch Only Touch peeling solution, and (reticular dermis peel) treatment for small Before the Only Touch peeling, patients place it in an small glass or ceramic lesions that are less than one centimetre should apply the Blending Bleaching in diameter. It is made up of a saponified, Cream twice a day for two weeks. The stabilised and adjuvated base solution Blending Bleaching Cream should be -Dip the chosen applicator in the of alpha hydroxy acids, antioxidants and combined with sun protection (SPF 20- peeling solution. Moisten the vitamins, to which physicians add 60). This preparatory procedure is applicator. Avoid excess peeling trichloroacetic acid (TCA) to reconstitute intended to avoid pigmentary rebound.
the peeling solution.
Before Only Touch Prescribe Blending -Do not let the peeling solution drip.
Bleaching Cream.Apply two times a day for 2 Weeks.
Applying Only Touch Only Touch is the recommended peeling for benign pigmentations or keratosis, Preparation of Only Touch Peeling The patient’s skin reaction must be under one centimetre in diameter, on checked the first time Only Touch is the face, décolleté, hands or forearms.
used. Apply it to just one small area and Suitable for Fitzpatrick phototypes I-IV.
-With a 1cc. syringe, extract the specified quantity of 80% m/m TCA wait to see the skin’s reaction.
Only Touch should not be used on larger (according to the instructions in the Only Touch should be applied with a lesions, not even partially. Only Touch fine cotton bud or wooden toothpick (for should not be applied in lesions of an -Inject the specified quantity of TCA very small areas), avoiding excess unknown or uncertain nature.
into the base solution included in the -Once the mix is ready (TCA + base 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 50 -Do not allow excess Only Touch Physicians should have patience with physician runs the risk of damaging the -Quickly touch the lesion to be treated solution to drip on the patient’s skin.
this process. At the first Only Touch surrounding skin, exposing it to an (like touching a telephone key).
-Wait until the acid solution has fully excess of acid.
-Be precise.
To obtain complete frosting, wait until -Noticeable frosting will appear quite the second application of Only Touch peeling solution, before the fourth Easy -If no such frosting appears, repeat the TCA session. Only Touch should be application cautiously a few minutes always applied in combination with Easy after the solution has dried.
-Note that the frosting will appear much more quickly on the face than Only Touch should be combined with on the hands, forearms and neck.
Easy TCA in four peeling sessions: one per week for face peeling, and two per Keratosis and Frosting week for the rest of the face.
Frosting Effect Keratosic Lesion Physicians should keep in mind that session, attempting to accelerate the Only Touch + Easy TCA keratosic lesions are less permeable to frosting effect by adding more peeling 4 Peeling Sessions = Once (Twice) a acid solutions than the surrounding solution on the keratosic lesion is not Week (See Graph Schedules) normal skin, and thus will be less permeable to Only Touch peeling Clinical experience demonstrates that Use different procedures for face, hands solution. For this reason, it will take the best solution is to wait until the next and forearms, and neck.
-Use the chosen applicator only once.
longer to see the characteristic frosting Only Touch peeling to get complete -Be very careful when applying the effect after treating a keratosic lesion frosting. If, at the first peeling session, with Only Touch.
excess peeling solution is applied in an attempt to obtain complete frosting, the 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 51 Only Touch + Easy TCA in combination Neck and Décolleté Procedure Physicians should apply Easy TCA For neck and décolleté treatment, Only immediately after treating the lesions Touch should be applied according to with Only Touch. TCA should be applied the basic steps explained above. Only until the whole face shows frosting Touch should be combined with the Only Touch combined with Easy TCA points. There is no risk of side-effects Easy TCA basic protocol until cloudy with Easy TCA application. Since Only frost or frosting points appear.
Touch produces a full protein coagulation in the lesions, the skin becomes locally Hand and Forearm Procedure impermeable. This provides a wide safety margin against side-effects.
Immediately after the frosting appears However, if Easy TCA is applied before and Only Touch has fully dried, apply applying Only Touch, there is a high risk the first of the four basic protocols of of producing an excessively deep lesion, the Easy TCA peel on the entire treated because Easy TCA would lessen the area – including the area where Only Only Touch combined with ETCA penetration of Only Touch.
Touch has just been applied, to obtain outside the face area an even result.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 52 - Do not use Only Touch on larger surfaces – not even partially.
Combine Easy TCA with SPF (20-60) - Only Touch is a deep peel.
- Avoid any contact between the skin sun protection depending on skin type.
- Skin Tech indications should be strictly observed.
and the concentrated TCA solution to Physicians should advise patients to - Incorrect use of Only Touch may cause problems.
be mixed with the Base Solution.
refrain from touching or scratching the - Respect the maximum diameter of 1 cm.
- Contact between the skin and Only normal scars that appear after the Touch should be very brief.
peeling procedure.
- Only Touch may be used for I–IV SkinTech Daily Care Fitzpatrick phototypes. Do not treat dark In between two peeling sessions, phototypes with Only Touch.
Actilift with dimethylaminoethanol patients should apply SPF (20-60) sun - Always combine Only Touch with Easy protection, after the Skin Tech Blending TCA, Blending Bleaching Cream and Vit.E Anti-oxydant Bleaching Cream, two or three times a Skin ageing <40-45 sun protection.
Re Nutriv ACE Lipoic Complex - Physicians should advise patients to refrain from scratching the scabs.
Skin ageing >40-45 When the peeling sessions are Re-Nutriv ACE Lipoic Complex complete, patients should continue to During the day (whole face) Persistent Local Erythema apply the Blending Bleaching Cream, combined with sun protection, for at Only Touch peeling sometimes results least six weeks. Thereafter, patients During the day (whole face) Blending Bleaching Cream in persistent local erythema. If it appears should use the recommended Skin Tech on the face, it lasts no fewer than two Blending Bleaching Cream anti-ageing cream.
(on hyper-pigmentation only) weeks. If it has resulted from an excessively deep peeling, it can last as Morning, evening, night Vit. E Anti oxydant long as three months. Erythema should 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 53 be treated with steroid creams, However, this same beneficial acid (TCA) penetration. It also fights group of glycoside plant constituents combined with Blending Bleaching mechanism could result in scarring if free radicals and protects the solution that form distinctive foamy, soapy Cream, twice a day. Patients must avoid Only Touch is applied on an area larger as well as the skin. Vitamin C stimulates solutions when combined with water.
exposure to the sun.
than one centimetre in diameter, or if collagen synthesis and promotes skin Like other glycosides, saponins provide patients scratch the exfoliated areas.
the skin with their water binding How Only Touch Works properties. They improve acid Only Touch is based on the action of a Active Ingredients penetration and bring evenness to the Citric acid is an alpha-hydroxy acid. It highly concentrated trichloroacetic acid peeling treatment. Saponins can enhances the peeling of trichloroacetic solution (TCA). TCA coagulates skin Trichloroacetic Acid (TCA) contribute to the post-peel healing acid, improving its skin penetration. It Trichloroacetic acid is not a component process as well, and there is some functions as a chelatin agent and of the base solution.
evidence that they also have protects the solution and the skin from It destroys all tissue structures up to the Adding the right amount of TCA to the antimicrobial benefits. Saponins foster free radicals. It is also an acidifying and level of the upper reticular dermis.
base solution (see product instructions the healing process.
buffering agent.
Adequate treatment of areas measuring on the box) transforms it into an less than one (1) centimetre in diameter adjuvated and stabilised Only Touch will allow for complete skin regeneration, Protects the skin and improves saponin After mixing the TCA solution and Base from the basal layer reservoir of Solution: 9 ml Only Touch. The number Only Touch Base Solution facilitates an Sodium Laureth Sulfate of possible treatments depends of the Surface active, emulsifying and wetting number of lesions to cover. If physicians Only Touch is an in-depth treatment, a in-depth peeling that reaches the agent that degreases and emulsifies use 0.2-0.5 ml. in each treatment, it is peeling that regenerates the skin from reticular dermis.
oils and fats and suspends dirt.
possible to treat between 18 and 45 under the lesion, ensuring definitive L-Ascorbic Acid (Vitamin C) As a component of the base solution, Saponins and Excipients L-ascorbic acid improves trichloroacetic Saponins are an extensive and varied 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 54 TCA + AHA + AntioxidantsThe Unideep kit includes: Unideep is a saponified and stabilised One or two peel sessions should be medium depth 23% m/m TCA pH<1 peel performed to promote deep skin that reaches the papillary dermis. To regeneration. This peel is suitable for obtain the Unideep peeling solution, the treatment of photoageing, acne, inject the required quantity of TCA into the base solution (see instructions chloasma, keratosis, and fine lines.
included in the product box). Unideep Unideep is a very flexible treatment, and is suitable for patients who desire quick can be used in many different ways. It results with few side-effects.
can be combined with a local deep TCA (Only Touch) or local phenol (Lip & Eyelid The Unideep kit includes one phial of Formula). It can also be applied locally base solution and two tubes of Post- (on the forehead, for example) while Peel Mask (with antioxidant and using Easy TCA on the rest of the face, stimulating effects) to be applied by the for a reduced effect on the patient’s one phial of base solution and two tubes physician immediately after the peel.
social life.
of Post-Peel Mask (with antioxidant and Also included are two applicators, one Hyperpigmentation Before Unideep Treatment stimulating effects) to be applied by the glass jar, and the instruction leaflet.
physician immediately after the peel.
Also included are two applicators, one glass jar, and the instruction leaflet.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 55 Directions for Use Applicator Preparation An uneven frosting will usually appear.
The kit comes with one large applicator: If necessary, apply another coat of break it into two pieces, and use just Unideep solution to produce an even, one piece. Hold the applicator with Local anaesthesia pinkish-white frosting. The frosting will tweezers, as shown in the photograph.
(truncal blocks) may be necessary for appear more quickly on thin, dry skin sensitive patients. For normal patients, than on thick, oily skin. Physicians will it is sufficient to cool the skin before have to apply more coats to thick skin applying the first Unideep coat and to achieve the same result.
between successive coats. For this purpose, use the 3M “Cold Pack” and Peeling Solution Preparation Cleanse the skin. Use Skin Tech Pre- To get Unideep peeling Applying the Unideep Peeling Peel Cleanser. Disinfect with alcohol.
solution, physicians Degrease the skin with acetone two or should add the right quantity of trichloroacetic acid to the base solution, according to the instructions found in the Unideep kit.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 56 After an even frosting has appeared, After Week 6 post-peel: Use the the incorrect use of Unideep.
How Unideep Solution Works apply 5 g. of Post-Peel Mask (50% of appropriate Skin Tech daily care cream the tube) to the face.
Never apply the TCA solution directly Unideep peeling solution (23% TCA m/m The patient should apply the rest of the onto the skin. The TCA solution must and other ingredients), coagulates the Post-Peel Mask tube to the face that be mixed with the Unideep Base epidermic and papillary dermic proteins, night, and also the next morning, after but not those proteins located on the cleaning the skin. The patient should vascular walls. This is why an even, see the physician on Day 3 and Day 6 Unideep can be used, according to the white pinkish frosting appears.
after the peeling.
instructions, on phototypes I to IV. To Cutaneous cells destruction triggers a treat darker phototypes, proceed with complex chain of reactions. The Post-Peel Daily Care Skin Tech Cream
caution. Prepare the skin two or three regeneration process comes from the Actilift with DMAE weeks before the procedure. Apply intact keratinocytes of the dermic Re Nutriv Lipoic Complex Blending Bleaching Cream twice a day.
papillae and also from the reservoir of -Apply Re-Nutriv ACE Lipoic Avoid solar exposition and apply a SPF keratinocytes in the pilosebaceous and Complex three times a day sweat glands units.
-Visit physician on Day 3 Apply Blending Bleaching Cream, twice -Day 4 to Day 7: Apply pure Vaseline Blending Bleaching Cream a day, during at least six weeks after After the peeling, a new epidermis -Visit physician on Day 6 Vit. E Anti - oxydant the peeling procedure.
develops. There is also an increased -Day 7 to Week 6 (at least): dermic stimulation, and fibroblasts Apply Blending Bleaching Cream (Skin produce more collagen, elastin, and Tech) and SPF 20-60 sun protection at Unideep is a papillary dermis peel. Skin Physicians should advise patients to Tech indications, proceedings, and refrain from touching or scratching the The Post-Peel Mask stimulates the skin methods should be strictly respected peeled area.
and stops the oxidative vicious cycle and followed. Problems could arise from (inflammation – free radicals). It shortens 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 57 the healing process, avoiding the skin with water-binding properties. There oxidation damage that comes with An alpha hydroxy acid. It enhances skin is some evidence that saponins also Keratolytic, used to treat dry skin; it classic post-peel inflammation. It also penetration, Functioning as a chelatin have antimicrobial benefits. They are increases skin permeability.
prevents against post-peel inflammatory agent and protecting the solution from also used for the skin, for even acid Silicium (Methylsilanol Manuronate): free radicals. It is also an acidifying and penetration, and to improve healing.
This oligo element is strongly linked to Unideep Base Solution allows for a safer buffering agent.
proteoglycans and papillary dermis peel.
The Post-Peel Mask has an antioxidant mucopolysaccharides, hyaluronic acid and chondroitin sulfate. Silicium plays Unideep Active Ingredients Protects the skin and improves saponin effect, stimulates skin regeneration, and promotes healing. Its action is very an important role in skin healing and is necessary to fight signs of ageing.
Trichloroacetic Acid (TCA) important for a safer papillary dermis Sodium Laureth Sulphate Adding the right amount of TCA to the peel. The post-peel penetration of base solution (see product instructions A tensio-active, emulsifying and wetting ingredients is dramatically modified when Vitamin C is a potent antioxidant. It on the box) transforms it into an agent with very good skin tolerance.
the peeling solution is applied works in water solutions, where it adjuvated and stabilised Unideep The molecular structure of the ingredient beforehand. The post-peel rate of captures free radicals; with this action, used by Skin Tech – sodium laureth penetration is much higher than the sulphate – differs from lauryl sulphate, Vitamin C prevents protein destruction.
normal skin rate. The skin is much more It also exerts a protecting role over other the skin irritant.
permeable during the close post-peel cellular antioxidants. This action is L-Ascorbic Acid (Vitamin C) Saponins and Excipients period: sebum and corneocytes no particularly valuable when there is an longer act as a barrier and hydrosoluble An antioxidant. Stimulates collagen Saponins are an extensive and varied increased number of free radicals, which ingredients can rapidly pass through synthesis and promotes skin group of glycoside plant constituents, occurs with wounds (whether they are this modified epidermis, so that high known as glycosides, which have infected or not) and in exfoliated areas distinctive foamy, soapy properties. As quantities of stimulating factors and after a peeling treatment.
a glycoside, a saponin can provide the antioxidants can reach the dermis.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 58 Skin Tech uses Magnesium Ascorbyl (GPX) [family of antioxidant enzymes] Vitamin E blocks oxidative chain Phosphate (MAP), which is the most which breaks down peroxides. It reduces reactions, inhibiting the formation of stable ascorbic acid derivative. On and This is an antioxidant with an hydroperoxides and acts as an lipoperoxyls in the cell, and protects inside the skin, phospatase, an abundant antityrosinase effect. It helps in treating intermediary on the cyclo-oxygenase nucleic acids and proteins (see section enzyme, quickly transforms it into hyperpigmentations and avoiding post- and lipo-oxygenase pathway, reducing on vitamins).
peel inflammation.
inflammation. It prevents the production Magnesium Ascorbyl Phosphate is better of inflammatory and immunosuppressive than ascorbyl palmitate (AP), used in cytokines, and boosts both cellular and A disinfectant, moisturiser, and stabiliser other preparations, because the humoral immunity. Combination with for vitamins, propylene glycol diminishes esterification of MAP occurs on the Vitamin E strengthens its protective corneocyte cohesion. This promotes the carbon where the enediol function is action and creates a tretinoin-like effect.
penetration of other active ingredients found (2nd carbon). This enediol is Pure cyclodextrin microencapsulated of the Post-Peel Mask.
responsible for the acidic and antioxidant retinol is used in this cream (see section Vitamin E (Tocopheryl Acetate) properties of the molecule. This is why on vitamins).
the esterification of this function protects Antibacterial. This has been used for MAP and allows for longer and better the disinfection of wounds and burns.
antioxidant efficiency. The enediol A trace element that accelerates skin This most stable ester of Vitamin E is function on carbon 2 of ascorbyle healing; its penetration is clearly automatically hydrolysed into pure palmitate is not protected by enhanced when combined with Vitamin E after cutaneous absorption.
esterification (see section on vitamins).
methionin. Creams based on selenium The acetate form is very interesting methionin enhance healing after laser because it constitutes a reservoir that resurfacing treatment or peeling, and slowly releases Vitamin E into the skin.
This is an alpha hydroxy acid. It is an prevent seborrheic dermatitis. Selenium Vitamin E traps the oxygen free radicals antioxidant with buffering and chelating is a component of Glutathion Peroxidase that can cause damage to the tissues.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 59 Vitamin H (Biotin – Coenzyme R Kit for two papillary dermis facial peels Base Solution + Post-Peel Mask + The metabolic action of the biotin is carried out by biotin-dependent enzymes, which act in the synthesis of the purines. It is a stable, water- and alcohol-soluble monocarboxylic acid, which acts as a co-enzyme or also as a "growth factor", even in very small quantities. Deficits of biotin are characterised by exfoliative dermatitis and hyperkeratosis with alopecia. Topical application of biotin lessens the secretion 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 60 Easy Phytic Solution Alpha Hydroxy Acid Mix It will not be outside the buffer potential or Intense Pulsed Light (IPL) treatment.
Cleanse the skin twice using Skin Tech of the skin (natural stabilising potential to Easy Phytic Solution combines the Pre-Peel Cleanser. Rinse with warm keep a constant pH).
benefits of three different alpha hydroxy water and dry.
Self-neutralisation occurs naturally and acids with the properties of phytic acid, automatically in the skin. The acid improving efficiency and minimising side- penetration is complete.
effects. The fact that it requires no Every acid molecule of the Easy Phytic neutralisation is an advantage for Solution is fully active.
physicians who wish to avoid the risks associated with other peeling treatments.
Easy Phytic Solution is an intraepidermic It is also an advantage for patients who peeling that stimulates the dermis, for do not wish to disrupt their social life patients who do not want visible signs of during the peeling treatment.
- Slow and progressive skin penetration Wide Safety Margin Quick and Easy
Easy Phytic Solution is a peeling based - Full action of all active principles on Skin Tech’s new release-controlled - No neutralisation required Cleaning and Skin Preparation It provides slow-release, progressive, complete penetration and full action of Indications and Advantages Avoid any additional skin preparation all the components of the solution.
before Easy Phytic. Do not use retinoids.
Although the solution has a very acidic Easy Phytic Solution is best indicated for Do not use any acid solution: acid pH 0.8, lower than its pKa, this new acne and the prevention and treatment solutions erode the corneal layer and alpha hydroxy acid (AHA) solution does of photoageing and hyperpigmentation.
allow the peeling solution to penetrate not require neutralisation by the It is also indicated as a maintenance into the skin more quickly, when Easy treatment after any other peeling, laser Phytic is supposed to penetrate slowly.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 61 Preparation and Application of Skin Tech cream must be applied Easy Phytic Solution immediately by the physician after the No frosting at all should appear. In the application of the Easy Phytic Solution.
Wear gloves to protect hands. Syringe event of accidental frosting, neutralise Following the peeling, after massaging, out 2.5 cc of Easy Phytic Solution, place the skin immediately. Use sodium apply the Skin Tech cream that is on a small cotton ball and gently apply bicarbonate solution: dissolve two appropriate to the case.
to the face.
tablespoons full in a dish of water.
The coats must be applied one after the other without rubbing the solution in and without letting it dry.
The number of coats depends on skin type: for thin and dry skin, one layer could be enough; for thicker skin, apply Apply the last coat after the patient begins to feel an itching sensation.
Skin Tech Cream
Massage the treated area to ensure that Actilift with DMAE the Easy Phytic Solution is evenly Re Nutriv Lipoic Complex applied. Do not neutralise. Do not remove the Easy Phytic Solution.
Blending Bleaching Cream Vit. E Anti - oxydant 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 62 Easy Phytic Solution Occlusion Under a Plastic Film Post-Peel Daily Care Total Number of Peels and The next morning, the patient’s skin can be cleansed normally. The same cream Discontinue the weekly peel sessions applied by the physician under occlusion when suitable results have been after the peeling session must be used, achieved. Use Easy Phytic Solution as combined with SPF 20-60 sun protection a maintenance peel, once or twice a depending on skin type.
month, as a long-term therapy. Patients should continue to use the prescribed Cover the whole area with clingfilm Long-Term Procedures Skin Tech cream.
(cellophane film) and leave for 20-30 minutes. Do not remove Easy Phytic Solution or the Skin Tech cream: let Easy Phytic Solution can be used as a them work until the following morning.
treatment or as maintenance care after Patients must be advised to refrain from other peelings. Repeat the peel once or cleansing or using other products on twice a week when Easy Phytic Solution the treated area until the next morning, is applied as a treatment. Repeat the and to refrain from scratching or touching peel until the desired effect is obtained.
Repeat once or twice a month when Easy Phytic Solution is used as maintenance care after a deeper peel.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 63 How Easy Phytic Solution Works its initial effect on ionic charges, which groups of keratin chains and inhibits the Post-peel occlusion prevents the is done through an inhibition of the reactions between them. This evaporation of trans-epidermic water Abnormal keratinisation causes many enzymes involved in the formation of “destabilising” effect seems to be and water soluble components. Skin different dermatological problems, such ionic links.
localised; it takes place at the deepest temperature increases locally, improving as ichtyosis, acne, psoriasis, eczema layers of the stratum corneum layers.
the penetration of the active principles.
and dry skin. Keratinisation problems For example, Easy Phytic Solution could This is why the active principles of Easy Hydric saturation of keratinocyte walls always consist of hyperkeratinisation – compete with sulphates and phosphates Phytic Solution improve the elasticity of modifies the geometry of the cells and never hypokeratinisation. The on the level of sulphotransferases, the stratum corneum and enhance its of the coefficient corneal layer/cream components of the Easy Phytic Solution phosphotransferases or kinases, partition. Pores are momentarily dilated.
involved in the formation of sulphated All of these effects increase the skin’s or phosphorylated For these purposes, alpha hydroxy acids permeability and allow for better (AHAs) are more efficient than the efficiency of the creams applied during sterols and lipids. This interfering action frequently used beta hydroxy acids (such the immediate post-peel period.
could reduce the quantity of electrically as salicylic acid). The alpha position of negative charged groups on the surface the HO group of AHA allows for better Easy Phytic Solution of keratinocytes and corneocytes. As a penetration between keratin chains than Regulates Keratinisation result, adhesion forces with amines or the beta position of beta HO acids.
Reduces Intercorneocitary Cohesion basic, positive charged aminated acids Enhances Hydration are weakened.
The application of Easy Phytic Solution Fosters Elasticity promotes the penetration of the active The way in which lactic acid fosters skin components of the creams used under alpha hydroxy acids) fight elasticity seems to be related to an occlusion after the peel, interaction with keratin polar groups.
hereby enhancing the treatment’s Easy Phytic Solution’s action on the Lactic acid is absorbed in the polar corneocytes seems to be secondary to 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 64 Easy Phytic Solution Active Ingredients into the epidermis and progressively Alpha hydroxy acids are natural Free radicals can attack the structures reaching the dermis, without ever that are supposed to regenerate the Alpha Hydroxy Acids exceeding the skin’s natural capacity to AHAs have multiple beneficial effects skin during the post-peel period.
Easy Phytic Solution is a neutralise acid or basic attacks (buffer when topically applied on the skin.
In the current scientific understanding multicomponent adjuvated and capacity). Easy Phytic Solution alpha of ageing processes, free radicals are saponified solution. It is made up of hydroxy acids progressively lose their generally considered to be one of the three alpha hydroxy acids (AHAs): aggressiveness in the skin, working to Phytic acid does not participate in the major factors responsible for cell glycolic acid, lactic acid, and mandelic their full capacity.
peeling process. It is a large molecule degeneration. It is important to fight free acid and phytic acid. With Skin Tech’s of inositol hexaphosphoric acid, able to radicals during the post-peel period.
time-release technology, their release According to current studies, alpha fight and neutralise free radicals. Every and action are progressive. Easy Phytic hydroxyl acids promote a thicker peeling produces inflammation After the Easy Phytic Solution’s three Solution does not require neutralisation epidermis, produce more symptoms: normal inflammation alpha hydroxy acids have made the skin or removal by the physician. The three mucopolysaccharids in the dermis, and liberates free radicals and causes permeable, phytic acid slowly penetrates alpha hydroxy acids have different rates promote better quality elastin. The vasodilation, which carries more oxygen it. Therefore, it is present in the skin of transepidermic penetration. The density of papillary dermis in situ, triggering the formation of more when free radicals are produced (parallel smallest, glycolic acid, penetrates first.
collagen is better as well. After a peeling free radicals.
to inflammation).
Then comes lactic acid, followed by with Easy Phytic Solution, patients report mandelic acid (the less volatile acid).
a tightening sensation and a visible Free radicals immediately bind to the By seeking out free radicals, we break difference in the look of the skin.
closest structure damaging it. Generally, the vicious cycle of inflammation These alpha hydroxy acids begin their a peeling promotes skin regeneration, vasodilation - production of free radicals, action at the level of corneocytes and but also induces the production of which occurs during the immediate post- keratinocytes. This allows the acids to damaging free radicals.
peel period.
continue their action, moving down 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 65 Precautions and Side-effects This penetration produces a dermal edema, which will disappear in two or Do not wear jewellery before the next three days without treatment. Should the morning (the acids could attack them).
edema, erythema or severe itching persist, it could be an allergy.
Avoid contact with the eyes and mucous In a small percentage of patients (around 2%, usually with thin and dry skin) Easy Phytic Solution may cause specific side- Red spots on the face of a 30-year-old patient, 50 ml bottle: 20 face peelings.
red spots on the face, which correspond two days after an Easy Phytic Solution peel. The punctual dermal edema disappears in two or three to a deep dermal penetration of the days without treatment.
acids of the Easy Phytic Solution.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 66 Blending Bleaching Cream Re-Nutriv ACE Lipoic Complex Vit. E Anti-oxydant 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 67 Blending Bleaching Cream Depigmentation cream Secondary hyperpigmentations in an Directions for use as a pre-peel armpit or groin intertrigo Depigmentation cream, without hydroquinone, pH 4 formulated, non Blending Bleaching is indicated to treat Blending Bleaching Cream can be used and prevent pigmentary rebounds due as a pre-peel daily care for patients with Can be safely used for the face and to chemical and physical peels, high phototype and sensitive skin, in abrasion, microdermabrasion, laser and sunny countries. Begin to apply Blending Bleaching Cream, twice a day, two or Eliminates the actual stock of epidermic three weeks before the peeling.
Blending Bleaching Cream is also useful Directions for use before Easy Avoids re-synthesis of melanin by as a preventive pre- peel regimen to avoid post peel hyperpigmentation in TCA, according to the abrasive Provides long term results high (dark) phototypes after peelings, occlusive protocol dermabrasions or lasers.
(allows about 30 days treatment) Blending Bleaching Cream should be Blending Bleaching Cream used as a pre-peel home care, before the Easy TCA abrasive-occlusive Blending Bleaching Cream can be used Blending Bleaching Cream can be used protocol, a peeling to eliminate stretch for a wide range of indications: alone, without any other treatment or be combined with peelings, lasers or marks, scars or to treat a décolletage.
To avoid post peel hyperpigmentations.
apply Blending Bleaching Cream, twice a day, two or three weeks before the Post inflammatory or hormone Easy TCA abrasive occlusive peeling.
dependant hyper pigmentations Melasma, and chloasma 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 68 Blending Bleaching Cream Use as maintenance home care Blending Bleaching Cream works on After Easy Phytic or Easy TCA differents steps of the melanin - begin the application of Blending Bleaching Cream 24 hours after the Get rid of existing melanin Melanines are very strong molecules After Unideep, Only Touch or Lip & that cannot be destroyed by chemicals in the melanocites and keratinocytes. In - begin the application of Blending any case, Blending Bleaching Cream Bleaching Cream as soon as possible allows a quicker elimination of the after desquamation, normally 8 days existing stock of intraepidermic melanin.
after the peeling.
It eliminates the epidermal stock of melanin by stimulating the epidermal In any case, Blending Bleaching
Picture the enemy: Cream should be used during at least
Melanin Polymer Structure 3 to 6 months.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 69 It´s antioxidant power limits the oxidative been formulated to allow long term Active ingredients steps of the melanogenesis.
treatments. To maintain a low level of melanin production and a high level of melanin elimination, the patient should keep using Blending Bleaching Cream to maintain long term results.
Lactic acid is an alpha hydroxy acid The continual use of Blending Bleaching (AHA). It exerts different effects: Cream during 6 – 12 months will provide long term efficiency.
- By weakening the bonds between Blending Bleaching Cream stimulates Results appear more progressively in corneocytes, it increases the skin’s The steps of the progressive synthesis the growth of normal keratinocytes the case of deeply located intradermic of melanin into melanosomes.Electronic permeability and makes the active microscope Bleaching effect located between basal layer ingredients penetration easier.
melanocytes. The same does not occur Always combine with a solar protection with melanocytes which do not multiply.
(SPF 20-60) to be applied at 09:00, - By stimulating the epidermal cell As a result of this specific effect, 11:00 & 15:00.
turnover, it helps to eliminate the already Antityrosinase molecules block different existing melanin.
steps of melanin synthesis by melanocytes, called melanogenesis.
- By stimulating dermal collagen - from Tyrosine to DOPA, Duration of the treatment synthesis, it attenuates skin ageing - from DOPA to dopaquinone.
symptoms. AHA are good moisturisers, - It also blocks the conversion of A depigmentation treatment has to be so they make skin look soft and smooth.
dihydroxyindole into indole 5,6 quinone.
understood as a long term programme and Blending Bleaching Cream has 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 70 Blending Bleaching Cream Antityrosinase Mixture One molecule of vitamin E protects 3000 Vitamin A stimulates mitosis specifically membrane phospholipids against in keratinocyte mother cells of the basal - Antioxidants can protect the skin The same does not occur with against free radical oxidation due to melanocytes which do not multiply. As a result of this specific - Antioxidants limit the post inflammatory effect, melanocytes appear more production of melanin.
dispersed between keratinocytes.
- Antioxidants also inhibit arachidonic This new mix and proportion are the acid, (a membrane constituent) basis of the “blending” effect.
It includes kojic acid, liquorice extracts, peroxidation, and the consecutive pro- Thanks to this effect, hyperpigmentations Morus alba extracts, and lactic acid.
inflammatory prostaglandins formation.
treated with Blending Bleaching Cream This antityrosinase mixture limits the enzymatic pathway of melanin This is able to concentrate the active production from tyrosine to indole components close to the basal layer and there, produce a reservoir of active products immediately around the Precursor of retinoic acid (Vitamin A) melanocytes. It enhances the efficiency of the Blending Bleaching Cream.
Vitamin E (Tocopheryl acetate) Keratinocytes synthesize retinoic acid in two steps from precursors to retinoic 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 71 Hyperpigmentations treated by 4 Easy TCA peels + Blending Bleaching Cream 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 72 Problems in young skin - Pre-peel & pre-laser care - Post peel & post laser maintenance care Cream can be applied as part of the after the peeling procedure. Apply Purifying Cream cleanses the skin from daily care maintenance after acne Purifiying Cream under plastic occlusion.
all impurities related to internal medical treatment. In order to maintain Let the cream work 15-30 minutes under imbalances at any age.
the obtained results, It can be used to prepare the skin before it should be used during at least six a peeling, before laser or before an Begin using the Purifying Cream the intense pulsed light Directions for use before peeling, morning after the first peeling session.
procedure against acne. It is part of the intense pulsed light (IPL), or laser daily care maintenance after any medical After IPL or laser In the case of badly damaged skin, Apply Purifiying Cream immediately after the peeling procedure.
Presentation: 50 ml tubes (approximately 30 days laser treatment against acne.
Purifying Cream can be used to prepare the skin before a peeling or laser Directions for use as a daily care Directions for use with long term treatment. When this is the case, the treatment to fight acne cream for young skin with use of Purifying Cream should start at least two weeks before the medical Purifying Cream is specially Purifying Cream is a daily care cream, procedure, once or twice a day, recommended as a daily care cream in pH 4, to fight problems in young skin.
Cleanse the skin before applying depending on the condition of the skin.
the case of long term acne treatment.
It is also highly recommended to prepare Purifying Cream. Use Skin Tech’s Pre- Purifying Cream should be applied twice the skin before a peeling, laser, or Peel Cleanser. Apply Purifying Directions for use after peeling, a day, depending on the condition of intense pulsed light (IPL) procedures Cream twice a day. In the morning, apply intense pulsed light (IPL), or laser the skin at least during six months, after against acne. It can be used as a Purifying Cream on the whole area, not which, it is possible to progressively maintenance care cream after acne just on the affected area.
reduce the frequency of use.
In the evening, apply Purifying Cream After Easy Phytic only on the affected area. Purifying Apply Purifiying Cream immediately after 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 73 Purifying Cream normalizes the The antioxydant effect is one of the Active ingredients keratinization and exfoliation rate.
Purifying Cream’s most important actions, because inflammation produces Blocks exfoliated corneocytes free radicals that damage the skin and can induce a vicious circle inflammation: Glycolic acid is a potent alpha hydroxy free radicals, that maintains the Prevents exfoliated corneocytes from inflammation by itself.
Since it accelerates the break down of sticking together.
It brings both epidermal and dermal old cells on the skin’s surface, it stimulation into action.
stimulates the turnover of epidermal Enhances the drainage from the follicular cells and favors the elimination of dead opening, removing material Moisturizer and anti itching effects: that clogs the pores.
accelerates healing and contributes to Glycolic acid also stimulates dermal the overall response to the cream.
collagen synthesis.
How Purifying Cream works Purifying Cream produces an Prevents the clogging of corneocytes.
antibacterial and antimycotic effect: it Enhances the drainage of the follicular Since skin genetic characteristics can eliminates or reduces the microorganism not be changed by peelings, laser, population, decreasing the level of It moisturizes, making the skin soft and intense pulsed light, or cosmeceutics, inflammatory extra-cellular products any correct cutaneous treatment should induced by microorganism proliferation.
It also increases the penetration of the be understood as a long term therapy.
other active principles of Purifying Cream That is why Purifying Cream has been Anti-inflammatory: reduces redness, into the skin.
formulated to allow pain and swelling.
long term treatment.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 74 Cyclodextrin encapsulated pure Vitamin A (Tretinoin precursor, sebaceous follicles, but with less side Retinyl palmitate) effects. Tea tree oil includes antibacterial Gram (+) and Gram(-) principles. It (Tocopheryl acetate) Cyclodextrin encapsulated pure Tretinoin, a retinoid, is the carboxylic exerts an anti-fungal effect against triclosan. Antibacterial and antimycotic.
acid of retinol, it’s precursor. In the skin, candida and different dermatophytes.
Acts as an anti-inflammatory substance.
tretinoin is a normal metabolite of retinol.
An anti-viral effect has also been Keratinocytes can transform retinol into described and it seems to be related to Tocopheryl acetate is used to constitute tretinoin. Tretinoin does not seem to viral adsorbtion. By suppressing the pro- a cutaneous reservoir of vitamin E in reduce sebum production. It’s major inflammatory mediator production, tea the skin, which is slowly released.
topic effect consists of epidermal tree oil can act as an anti-inflammatory.
(For additional information see vitamins stimulation increasing the rate of Even if this extract is an oil, it does not desquamation. It prevents the make the cream oily.
corneocytes clogging and enhances drainage of the follicular openings. In Glycyrrhetinic acid recent clinical papers, tretinoin has been said to have, “a superior ability to A moisturizer, an antipruritic and an anti- eradicate existing comedones and prevent the formation of new ones”.
Tea tree oil (Melaleuca alternifolia) Tea tree oil has a bactericidal or antiseptic effect similar to benzoyl peroxide that kills bacteria in the 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 75 Re-Nutriv ACE Lipoic Complex Anti ageing cream Directions for use as anti ageing protection cream (SFP 20-60), to be applied ten minutes after the Skin Tech Re-Nutriv ACE Lipoic Complex, pH 6, can be used on the face and body Antes de aplicar Re-Nutriv ACE Lipoic Evening: apply Re-Nutriv ACE Lipoic Complex, se aconseja limpiar la piel con -Anti Ageing cream la espuma no irritante de SkinTech, Pre -Stimulates and moisturizes the skin Peel Cleanser.
-Blocks free radical formation Morning: apply DHEA PHYTO and follow -Boosts the skin’s barrier function with a sun protection cream (SFP 20- 60) to be applied ten minutes after the Skin Tech cream.
Presentation: 50 ml tubes for approximately 30 Evening: apply Re-Nutriv ACE Lipoic days treatment.
Destructuration of the skin’s -Prevention of skin ageing for all ages.
membranes by free radicals -Suitable to repair sun damaged and Directions for use In combination with other smoker's skin.
Cleanse the skin before applying Re- -Prevention of oxidation damage after Nutriv ACE Lipoic Complex.
sun or chemical burns.
After Easy Phytic or Easy TCA treatment The use of Skin Tech non irritative foam -Suitable for use after sunburn.
begin applying Re-Nutriv ACE Lipoc Pre-Peel Cleanser is recommended.
Complex 24 hours after the peel.
-Post laser, post chemical or physical peel antioxidant moisturizing that can Morning: apply Vit. E Antioxydant and reduce the duration of an erytheme.
follow the application with a sun protection cream (SFP 20-60), to be 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 76 Re-Nutriv ACE Lipoic Complex After Unideep treatment apply Re-Nutriv Thanks to its vitamins, Re-Nutriv ACE Active ingredients ACE Lipoic Complex on days 1 to 3 Lipoic Complex preserves the skin’s (Pure cyclodextrin encapsulated after the peel and from the 6th week enzymatic (like superoxide dismuthase Antioxidants and vitamins are among – SOD), and non enzymatic (like vitamin the active ingredients of Re-Nutriv ACE After Only Touch or Lip & Eyelid E) natural defenses from free radical Lipoic Complex.
Topically applied, ascorbic acid acts as Re–Nutriv ACE Lipoic Complex includes an efficient free radical scavenger. It begin applying Re-Nutriv ACE Lipoic Stimulates and moisturizes the skin.
bio available forms of A,C and E vitamins interacts with other fat soluble Complex as soon as possible after the in their most stable structures ready for antioxidants which are are in the cell Has an anti -inflammatory effect.
a sustained release.
membrane. It can convert inactivated vitamin E back to it’s active form.
After laser or IPL treatment Inhibits melanin synthesis.
begin applying Re-Nutriv ACE Lipoic Complex as soon as possible after the Stimulates collagen metabolism.
Blocks free radical formation.
How Re-Nutriv ACE Lipoic Protects the skin against UV radiation.
Pure cyclodextrin encapsulated retinol Re-Nutriv ACE Lipoic Complex directly (pure vitamin A).
protects the skin against free radical Regulates the skin’s pH.
Precursor of tretinoin (which is the carboxylic acid of retinol ).
Boosts the skin’s barrier function.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 77 Vitamin E (Tocopheryl acetate) Alpha Lipoic acid Ceramides are fundamental in protecting the integrity of the skin. They make up Tocopheryl acetate is the most stable approximately 40 % of the fatty acids ester of vitamin E. It is automatically within the cells. Ceramides are also hydrolysed into pure vitamin E after present in cell membranes, where they It is an unusual "vitamin like" antioxidant.
create an impermeable, insulating coat Active on both lipid and water phases.
for the outer skin layers preventing Very active as a -OH radical quencher.
The acetate form is very useful for topical cutaneous ageing symptoms.
use, because it constitutes a reservoir Ceramides can help to prevent skin Lipoic acid scavenges peroxyl, ascorbyl that slowly releases vitamin E into the ageing symptoms. They can contribute and chromatoxyl radicals. It protects skin. Tocopheryl acetate ester to repairing skin damage resulting from natural non enzymatic antioxidant accumulates in the skin and is exposure to different chemical products, defenses (like vitamin E and C). It also progressively hydrolysed into pure such as soaps, that erode the skin’s preserves natural enzymatic antioxidant keratin layer. Ceramide III is one of the defenses (GPX, SOD, catalase). It’s skin’s lipids. It is an excellent skin anti-inflammatory properties are useful Vitamin E traps oxygen free radicals moisturizer and also boosts the skin’s in the treatment of post laser and post that can damage tissue. It also blocks barrier function.
peel erythme.
oxidative chain reactions, inhibiting the formation of lipoperoxyles inside the cell Glycyrrhetinic acid and protecting nucleic acids and proteins from oxidation.
It is a moisturizer, an antipruritic and Vitamin E fights free radicals.
has anti-inflammatory effects.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 78 Vit. E Anti - oxydant Moisturizer & Anti ageing - Vitamin E Ceramides & Biosaccharides - Natural Moisturizing Factor Directions for use as daily care How Vit. E Anti-oxydant works Vit. E Anti-oxydant is a moisturizer and The immediate and long term hydration an anti ageing protective cream.
Apply Vit. E Anti-oxydant daily, in the Suitable for daily skin care. It is a pH 6 morning and in the evening, after Immediate moisturizing by the formulated cream suitable for all skin cleansing the skin restoration of superficial lipids and skin and before applying make-up.
Long term moisturizing provided by the Directions for use after peeling biosaccharides. As a result,Vit. E Anti- oxydant fights the problems that give rise to first wrinkles. It prevents skin Presentation: 50 ml tubes for approximately 30 After Easy Phytic or Easy TCA: days treatment.
begin applying Vit. E Anti-oxydant the damage caused by dryness. It is also -Skin protection from free radicals and morning after the peel.
an anti-irritant and anti itching cream.
After Unideep, Only Touch or Lip & -Suitable for very sensitive skin.
begin applying Vit. E Anti-oxydant as -Provides an intense moisturizing effect soon as possible.
after peels, laser, intense light, abrasion Directions for use after laser or IPL: begin applying Vit.E Anti-oxydant inmmediately after the procedure.
Then continue applying it daily, about six times a day, to keep the skin moist.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 79 Protection against environmental Active ingredients Vitamin E is one of the most important Ceramides make up approximately 40% With its double filmogenic effect, (from Vit. E Anti-oxydant components. Vitamin of fatty acids within the cells. Also biosaccarides and filmogenic E is a great antioxidant. It protects the Vitamin E (Tocopheryl acetate) present in cell membranes, they create polymer),Vit. E Anti-oxydant prevents cell membrane and intracellular Tocopheryl acetate is the most stable an impermeable, insulating layer for skin damage caused by external organites. It prevents the oxidative ester of vitamin E. It is automatically outer skin layers. Their presence aggression such as dust, dirt and soot destruction of constitutional hydrolysed into pure vitamin E after prevents skin ageing, since they are polyunsaturated free fatty acids of cell cutaneous absorption. The tocopheryl able to repair the skin damage resulting Protection against internal aggression membranes, which are very sensitive acetate form is very useful for topical from exposure to different chemical Vit. E Anti-oxidant disarms free radicals.
to oxidation. Vitamin E stabilizes the use, because it is used to constitute a products, such as soaps. Ceramide III It protects SOD, superoxide dismutase, membranous lipids and protects the cutaneous reservoir of vitamin E in the specifically boosts the skin’s barrier Vit. E Anti-oxydant limits the production cellular walls against oxidative skin which is slowly released.
of malone dialdehyde linked to ageing, thanks to its action on collagen glycation.
Polysaccharides made of special sugars: Anti inflammatory and anti itching effect fucoses. They produce immediate When topically applied, vitamin E inhibits moisturizing due to their filmogenic arachidonic acid peroxidation and the effect. Biosaccharides produce a subsequent formation of prostaglandins.
sustained moisturizing effect, due to Additional to this anti-inflammatory effect, slow sugar metabolic degradation.They glycyrrhetinic acid fights itching. Vitamin also have an anti-inflammatory effect.
E stabilizes lysosome membranes and prevents histamine liberation.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 80 Vit. E Anti - oxydant Natural Moisturizing Factor (NMF) The Natural Mosturizing Factor (NMF) is part of the skin. It makes up about 20-25% of the keratinous protective layer. Different formulas of this natural component can be found. Skin Tech use a mix of aminoacids, hexoses, hexylene glycol, urea, aspartic acid, and hexylnicotinate. The NMF functions as a stabilizer of the water content in the corneocytic layers. It retains the water content and prevents skin dryness.
Glycyrrhetinic acid It is a moisturizer, which also has an anti-itching and anti-inflammatory effect.
A filmogenic polymer that protects the skin against external aggression.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 81 Anti ageing - DHEA precursor Directions for use as anti ageing After Unideep, Only Touch or Lip Cleanse the skin before applying DHEA- Begin applying DHEA-PHYTO as soon PHYTO. The use of Skin Tech’s Pre- as possible after the peeling procedure, Peel Cleanser is highly recommended.
about eight or ten days.
DHEA–PHYTO, pH 6 is an anti ageing, Apply DHEA-PHYTO in the morning.
moisturizer and protective cream. It´s Combine with solar protection (SPF20- basic principle is precursors of Directions for use combined with 60) to be applied 5-10 minutes after DHEA –PHYTO.
laser or intense pulsed light DHEA–PHYTO is suitable for daily skin In the evening apply Re-Nutriv ACE Lipoic Complex.
Begin applying DHEA-PHYTO as soon 50 ml tubes (enough cream for approximately 30 as possible after the peeling procedure.
Directions for use combined with Immediately after the procedure, in the case of intense pulsed light.
Prevention of skin ageing (face, neck, decolleté, hands, fore arms) for patients After Easy Phytic or Easy TCA over 40 years old, with or without Begin applying the DHEA-PHYTO the previous peeling, laser or intense light.
next morning after the peeling procedure.
This moisturizer protects the skin against declines with age some free radicals.
Favours skin immunity.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 82 Dehydroepiandrosterone (DHEA) is a Active ingredients: Both DHEA and the steroid yam extract, Natural Moisturizing Factor (NMF) steroid which declines with age, but are significantly active as antioxidants.
without a well-known systemic activity.
Natural DHEA precursor NMF naturally exists in the skin. It makes Topically applied, it has a powerful up about 20-25% of the skin protective protective effect. It allows the skin to be better moisturized and avoids the Ceramides are important in protecting Skin Tech NMF is a mixture of amino dryness that comes with ageing. It acts the integrity of the skin. They make up acids, hexoses, hexylene glycol, urea, against every day damage, by approximately 40 % of the fatty acids aspartic acid and hexylnicotinate.NMF maintaining skin immunity.
within the cells. These lipids are also stabilizes the water content of the DHEA lowers IL-6, one of the pathogenic Dioscorea villosa (Wild yam) present in cell membranes, where they corneocytary layer and prevents elements in inflammatory and age create an impermeable, insulating layer related diseases involved in stress and Precursors of dehydroepiandrosterone for the outer skin layers. It´s presence infection. DHEA is a very potent catalase prevents skin ageing symptoms, Glycyrrhetinic acid inducer, which neutralises hydrogen repairing skin damage resulting from A moisturizer, an antipruritic and an anti- peroxide-related injuries and can up exposure to various chemical products, regulate immune response.
such as soaps that damage the keratin Dioscorea villosa extracts.
Dioscorea includes more than 600 III is one of these skin lipids that A filmogenic polymer that protects the different plant species. From Dioscorea moisturizes the skin and boosts the skin against external aggression.
villosa, commonly know as wild yam, it skin’s barrier function.
is possible to extract diosgenin, which can be used to obtain precursors of cortisol synthesis as well as steroid 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 83 Vitamins for the skin Topically applied vitamins for skin regenerationA significant amount of scientific data elimination of aged cells (apoptosis), – Protects against damaging UV rays – Tech uses cyclodextrins encapsulated supports the important role of free and allows new keratinocyte formation.
prevents wrinkle formation pure retinol or other retinoid derivatives.
radical-induced injury in skin ageing.
It regulates cellular migration from the These ingredients are able to easily Fortunately, there are a number of epidermal basal layer, a basic step in Collagen synthesis penetrate the skin and do not have any scientific results proving the beneficial skin regeneration.
irritating effects.
effects of topical use of antioxidants To carry out these functions, Vitamin A One of the most common characteristics Cyclodextrin encapsuled pure retinol against free radicals. Animal and human could function as a signal for the binding in aged skin is the degradation of support reaches the skin´s deepest layers studies have proved that topically of the epidermal growth factor to skin structures (connective tissue). This without being exposed to oxidation.
applied antioxidants can disarm free cells. It could be related to certain genes process takes place in normal aged skin Considering the main steps of vitamin radicals and improve skin appearance.
as well as in photoaged skin. A reduction A synthesis, the use of cyclodextrin They can even slow or reduce the signs in collagen synthesis is, in both cases, encapsuled pure retinol seems of ageing. Among the more efficient the base of the deteriorating process.
topical uses of antioxidants are a number Vitamin A topical use effects (Pure That is why topically applied vitamin A’s of vitamins.
stimulating effect on fibroblasts improves Antioxidant – fight free radicals – cutaneous regeneration.Topically applied Vitamin A (Retinol) reverses the signs of ageing vitamin A can reduce collagenase levels.
Stimulates re – epithelization – promotes Cyclodextrins encapsuled pure retinol post peeling regeneration – Thickens - The irritating effect of topical retinoic It has been established that topical use the epidermis – Stimulates dermal acid comes from large quantities applied of vitamin A and its retinoid analogs fibroblast growth – increases collagen, topically, far from target cells where it favours skin renewal, by increasing the GAGs, and elastin synthesis – Improves can naturally be found. Depending on rate of mitotic division. Vitamin A induces skin elasticity – fresher skin aspect the preparation, Skin Tech uses a healthy differentiation of the basal Reduces levels of collagen degrading cyclodextrins encapsulated pure retinol layer cells. It also participates in the enzymes – preserves dermis structure or other retinoid derivatives. These 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 84 Vitamins for the skin Main steps of vitamin A synthesis new proportion between keratinocytes fibroblasts: a very important function in and melanocytes favoring keratinocytes.
skin wound healing.
Retinoic acid is synthesised inside the Cyclodextrin encapsuled pure retinol is The end result is the desired fading of It is needed in the incorporation of prolin keratinocytes, near the receptors. The one of the ingredients of the Skin Tech, to collagen: acts as a co-factor of prolyl first step is the transformation of retinol Post Peel Mask. Topically applied retinol and lysy hydroxylases.
into retin aldehyde, and then into retinoic thickens and moisturizes the epidermis Vitamin C is also important for the acid, both steps thought enzymatic and, as after a peeling the corneal layer maintenance of the dermis structure.
regulation. Retinoic acid has been said is thinner, the skin becomes smoother.
Vitamin C takes part in elastin synthesis.
to modulate the transcription of certain Retinol also inhibits cell clogging at the Collagen III production booster (anti pore level of pilo sebaceous units Vitamin C has important physiological genes which codify for important ageing). Reverses the signs of ageing.
avoiding comedone formation.
effects on the skin: a deficit of vitamin C in the human diet gives rise to Since ascorbic acid is unstable in water Blending Bleaching Cream hyperkeratosic folliculitis and problems solutions, and does not dissolve in lipids, with wound healing. Vitamin C takes Skin Tech uses cyclodextrin Skin Tech includes retinyl palmitate in part in the skin cells energetic encapsulated ascorbic acid, or Blending Bleaching Cream to get the metabolism and in collagen synthesis.
Magnesium Ascorbyl Phosphate (MAP) benefit of it’s stimulating effect upon which is the most stable and hydrophile keratinocyte mother cell mitosis. It’s not derivative of ascorbic acid. On and inside the same with melanocytes; their the skin, it is quickly transformed into number remains the same. As a result vitamin C by the action of a phosphatase of this uneven cellular multiplication, enzyme which is very abundant on the melanocytes become dispersed among the increased number of keratinocytes.
Vitamin C modulates the transcription Magnesium Ascorbyl Phosphate (MAP) It is the so called “blending” effect: a of collagen III synthesis genes.
offers better antioxidant performance It stimulates collagen synthesis by 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 85 than ascorbyl di-palmitate (from ascorbic -MAP can be used on sensitive skins acid and palmitic acid), frequently used and also as part of peeling procedures.
in topic preparations.
-MAP is more easily absorbed into the In the case of MAP, the second carbon, skin cells than ascorbic acid.
the one with the enediol function is esterified. It is protected and less -Inside the skin MAP inhibits tyrosinase exposed to degradation. Since this function is responsible for the acidic and for the antioxidant properties of the -Protects the skin against UVA and UVB molecule, MAP allows a longer and light or sun related ageing.
better antioxidant efficiency in the skin.
On the contrary, the enediol function of -Preserves vitamin A from oxidation.
ascorbyle palmitate is not protected and is exposed to oxidation. Inside skin cells, -Vitamin C antioxidant effects.
MAP is converted into ascorbic acid, magnesium, and phosphorum, important -Free radical scavenger.
elements used in different metabolic -Improves re – epithelization.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 86 Vitamins for the skin absorption, it is hydrolysed into pure Antihistaminic activity (Tocopheryl acetate) Vitamin E stabilizes the lysosomal Skin Tech’s Vit .E Anti -oxidant main membranes, it helps to prevent ingredient is tocopheryl acetate. Topically histamine release and limits post UV applied tocopheryl acetate is used to erytheme duration.
Vitamin E is a very important antioxidant constitute a cutaneous reservoir of molecule: it protects the cell membrane vitamin E, which is slowly released into Vitamin E protects superoxide and intra cellular organites from the skin. There, it traps oxygen free dismutase, an enzyme able to neutralize oxidation. It stabilizes and protects cell radicals that can damage tissue. It also membrane lipid components against blocks oxidative chain reactions inhibiting the formation of lipoperoxyles It limits the formation of protein cross Vitamin E blocks the production of inside the cell.
lipoperoxyles inside the cells that originate from oxidative chain reactions.
One single vitamin E molecule is able Vitamin E limits the production of malone It also protects nucleic acids and to protect 3000 membran phospholipids.
dialdehyde, directly linked to ageing due proteins. It inhibits peroxidation of a to its action on collagen glycation.
membrane component: arachidonic acid.
Vitamin E also blocks the consecutive pro - inflammatory prostaglandins It accelerates the healing of burns.
Tocopheryl acetate is the most stable Vitamin E. plays the part of an anti - ester of vitamin E. After cutaneous inflammatory component which is very interesting during the post peel period.
030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 87 Baumann Leslie, Cigarettes and aging Biochem Pharmacol (1987) 36:919-24.
measurable acid levels of irritation.
response to "The politics of skin, Cosmetic Dermatology: Principles J.Invest.Dermatol, (1995)105, 4; 554-6.
Naysaying". Anti-aging medical and Practice, Chap 4, 21-23, Darr, D, et al., Effectiveness of therapeutics, Vol I, Health Quest Mc Graw Hill, 2002.
antioxidants (vitamin. C and E) with and Kibbe, Arthur H., Handbook of without sunscreen as topical Pharmaceutical Excipients, 3rd edition, publications, (1997),Chap 9, 75-81.
Baumann Leslie, Hormones and aging photoprotectants. Acta Derm.Venereol 2000. American Pharmaceutical Regelson William, MD, DHEA, Melatonin skin, Cosmetic Dermatology: Principles (1996) Jul;76 (4), 264-8.
Association.
and hormone replacement updates, Anti- and Practice, Chap 5, 25-28, aging medical therapeutics, Vol III, Mc Graw Hill, 2002.
Duell, Kang,Voorhees, Unoccluded Lactic acid and lactates: natural active retinol penetrates human skin in vivo ingredients. Euro Cosmetics,(1998) Health Quest Publications, (1999), Chap Baumann Leslie, Acne, Cosmetic more effectively than unoccluded 26, 191-196.
Dermatology: Principles and Practice, retinyl palmitate or retinoic acid.
Shai, Maibach, Baran, Recent scientific Chap 9, 55-61, Mc Graw Hill, 2002.
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characteristic of retinoic acid but without Dehydroepiandrosterone (DHEA) A 030923_SKI_RZ_GB.FH11 Wed Jul 04 17:00:50 2007 Página 88 Table of contents Easy TCA basic protocol .2-28 Daily Care .66-83 Easy TCA Abrasive protocols .29-40 Blending Bleaching Cream .67-71 Easy TCA combined with other treatments .40-42 Purifying Cream .72-74 Easy TCA Advantages.43-45 Re-Nutriv ACE Lipoic Complex .75-77 How Easy TCA works.45-46 Vit. E Anti – oxydant.78-80 Active ingredients and presentations .47-48 Vitamins for the skin.83-86 Easy Phytic Solution.60-65

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Kca eagle mar 2008 final.pub

VOLUME 4, ISSUE 2 We're on the Web at: JAMES TERRONES, KCA PAST PRESIDENT, SEEKS POSITION O N A C A D ELEGATE A SSEMBLY I N THE AREA OF M EMBER- AT-LARGE ETHNIC MINORITY tation Process. James received son County Department of a B.A. in Criminal Justice/ Corrections Juvenile Deten- Police Administration from Parkville University. James began his career with James is the Past-President of

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Nombre: Lola Bravo Ballester y Laura López Flores Curso: 1º Bachillerato 2. Justificación de proyecto…………………………….…….……. Página 4 3. Objetivos………………………………………………………… Página 4 4. Metodología…………………………………….……………… Página 5