Theralogix newsletter v1_iss6
thoughtful, intelligent and safe information for your health
Vol 1, Issue 6
Saw Palmetto for
Symptoms of BPH
What is BPH?
BPH (Benign Prostatic Hyperplasia) is
What can you do?
defined as noncancerous enlargement of the
If you feel like you've developed a problemwith BPH, there is good news! There are
prostate. As men age, it is common for
treatment choices for decreasing your
their prostates to grow. Researchers are not
symptoms. Conventional treatments forBPH include surgery (TURP- transurethral
sure why this growth occurs, but by age 60,
resection of the prostate is the standard surgicaltreatment) and/or prescription medications.
over half of all men have symptoms of BPH.
There are two general types of medicationsprescribed for BPH: Alpha-blockers (Hytrin,Cardura, Flomax, and Xatrol) and 5-alpha-
The prostate is a small gland that sits just
reductase inhibitors (Proscar and Avodart).
Alpha-blockers relax the smooth muscles in
below the bladder. The central area of the
the urinary tract and prostate, thus
prostate encircles the urethra (the tube that
making it easier to urinate. 5-alpha-reductase inhibitors block the
carries urine out of the bladder). As BPH
conversion of testosterone to
progresses, the prostate grows and squeezes
dihydrotestosterone, a hormone thatstimulates the prostate to grow.
the urethra, thus potentially causing
These drugs shrink the prostate andtherefore reduce the pressure on the
bothersome symptoms. These symptoms
urethra, which decreases the urinary
can include frequent trips to the bathroom
tract symptoms. Proscar can take up to 18 months to workand may cause side-effects, such as loss of sex drive and
(especially during the night), an urgency to
erectile dysfunction, in approximately 6-19% of patients.
urinate, a feeling of fullness in the bladder
Because of the expense and possibility of side-effects with
after urination, a hesitation before urine
drugs and surgery, many men have tried herbal supplementsto help reduce their urinary tract symptoms. Although
flow begins, and weak urinary stream.
many herbal products are touted as "cure-alls," the most well
(continued on back)
Beware –
the claim on the bottle label. The range of
The FDA and dietary supplements:
differences from the stated dose was
Why is there such variation in quality and
between -97 to +140%, and half of the
accuracy of these supplements? Because
all saw palmetto
sampled brands contained less than 20%
the FDA does not require that dietary
of the stated dose. In 2002,
supplements be tested before they are
products are not the same!
Consumerlab.com examined 14 saw
released for sale to the public. Dietary
palmetto supplements and found that only
supplements are not regulated in the same
nine of the 14 passed their testing. The
way as pharmaceuticals (medications) and
Recent studies have shown that many
other five did not pass because they were
do not have to undergo the rigorous
"mass marketed" saw palmetto
either contaminated with other
quality testing that medications do.
supplements are poorly made and do not
ingredients, or contained too little of the
Instead, the FDA considers them to be
actually contain the amounts of
active ingredient. Because the quality of
"foods" and requires essentially no purity
ingredients listed on the label. In a study
mass market saw palmetto supplements
or content testing. Quality control is not
published in the Journal of Urology in
varies so greatly, many men are not
well-regulated, and the result is a lack of
June 2002, independent lab tests were
getting the amount of active ingredients
content accuracy, purity, and safety in
conducted on popular brands of saw
needed to see results.
many dietary supplements for sale today.
palmetto supplements. The actual contentof saw palmetto extract was compared to
What can you do? (continued from front)
What to look for when choosing a saw
researched herbal supplement for decreasing
urinary tract symptoms is saw palmetto. Thisherbal extract has been an accepted treatment
When purchasing a saw palmetto supplement, you should be aware of a
for BPH for decades in Europe. It is derived from
the berries of the saw palmetto plant, Serenoarepens, a shrubby palm found in the coastal
1) Seal of certification- the supplement should be independently certified
regions of Southeastern U.S. The active part of
for content accuracy, safety, and freedom from contamination by a third
the plant is the sterols and fatty acids found in
party certification. If a supplement has been certified, the certification
the berry. Many studies have shown that saw
seal (such as USP® or NSF® International) will appear somewhere on
palmetto improves urological symptoms to a
the supplement bottle's label.
greater extent than placebo. In a large
2) Standardized extract- saw palmetto extract should be standardized, i.e.
randomized trial of 1,098 men with BPH, saw
standardized to contain a certain percentage of fatty acids, the active
palmetto was roughly equal to Proscar in
ingredient. The total amount of fatty acids in the product is important
reducing urinary symptoms.
and supplements should consist of approximately 270-360 mg of fattyacids in a daily dosage.
Saw palmetto is safe, causes virtually no side-
3) The form of saw palmetto and the type of extraction process used is
effects, and does not falsely lower PSA levels
important. Most studies of saw palmetto have used standardized extracts,
(which could mask the diagnosis of prostate
not the whole berry or other forms found in some supplements. An
cancer). Today, most urologists agree that saw
extraction process called supercritical CO
palmetto is a safe, effective approach to urinary
2 extraction has been shown to
produce a very accurate and consistent final product.
tract symptom relief.
High Quality extract
Other herbal extracts for
chosen for NIH trial:
Questions or Comments?
The National Institutes of Health chose
Although the most evidence exists for saw
Contact Us
Indena, SA, a European company, as the
palmetto, there are some studies suggesting
supplier of saw palmetto extract for its large
that other botanicals may also be beneficialin the treatment of BPH. These include
Theralogix, LLC.
clinical trial testing the effectiveness of saw
Pygeum africanum, Beta-sitosterol
401 East Jefferson St.
palmetto extract on urinary symptoms in
preparations, Nettle root, and rye pollen.
men with moderate to severe BPH. Indena
However, the existing studies on these other
Rockville, MD 20850
uses a supercritical CO2 extraction process
to produce its saw palmetto extract. Indena
plant extracts are less thorough than those
is the supplier of saw palmetto extract for
on saw palmetto and it is difficult to draw
the new Theralogix saw palmetto extract
conclusions from them. More studies need
301-610-9941 Fax
product, Prostate SR.
to be conducted to determine the safety and
efficacy of these products.
Source: http://www.theromega.com/about-theralogix/theralogix-newsletter/the-benefits-of-saw-palmetto/
ijpcr.net
C. Velmurugan,et al / Int. J. of Pharmacology and Clin. Res. Vol-1(1) 2016 [1-7] International Journal of Pharmacology and Clinical Research (IJPCR) IJPCR Volume 1 Issue 1 Jan-Mar - 2016 Research article Pharmacology research Anthelmintic activity of leaves of different extracts of Gossypium
Op-jeen150272 1.8
Journal of Economic Entomology Advance Access published September 5, 2015 Spray Toxicity and Risk Potential of 42 Commonly Used Formulations of Row Crop Pesticides to Adult Honey Bees (Hymenoptera: Apidae) YU CHENG ZHU,1,2 JOHN ADAMCZYK,3 THOMAS RINDERER,4 JIANXIU YAO,1 ROBERT DANKA,4 RANDALL LUTTRELL,1 AND JEFF GORE5 J. Econ. Entomol. 1–8 (2015); DOI: 10.1093/jee/tov269