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i n t r O d u c t i O nDebriefing has been shown to improve clinical behavior during cardiac resuscitation and, as such, has become a recommended procedure in the 2010 European Resuscitation Council Guidelines for Resuscitation. Edelson and colleagues reported that the number of patients achieving return of spontaneous circulation (ROSC) at a university hospital in the Midwest of the US increased from 44.6% to 59.4% (p=.03) when weekly debriefing sessions were conducted.1 This guide has been developed to provide guidelines for debriefing the key measures of care that can have a significant impact on outcomes from sudden cardiac arrest (SCA). The key components of an optimal in-hospital cardiac In-hospital resuscitation can be generally characterized arrest response: as a disorganized, stressful event that lacks definitive 1. Early recognition that the patient is deteriorating or leadership. Inexperienced providers and crowds of has become unresponsive.observers are also common, as are poor outcomes. Because on average, just 17% of all in-hospital arrests 2. Bystander response. At the risk of overstating the result in survival to discharge, one wonders if the low rate issue, with the exception of the Emergency Department of survival is due to the process or the patient. Since the (ED) or critical care staff, the first responder in a hospital release of the 2005 ERC Guidelines, where emphasis is rarely more experienced than an educated bystander was placed for the first time on high-quality CPR with who comes upon a sudden cardiac arrest victim longer periods of compression and fewer ventilations, outside of the hospital. It is important that all staff are we have begun to deconstruct the response to in-hospital empowered to act, even if that means doing nothing cardiac arrest. Early data indicate that survival from more than immediately starting high-quality CPR. At a in-hospital cardiac arrest can be improved (i.e., the minimum, the second responder should bring the crash current low rate of survival from in-hospital arrest cannot cart to the room, deploy the defibrillator pads, and turn be entirely attributed to unsalvageable patients). It has on the defibrillator in anticipation of the arrival of the become evident that obtaining a good outcome requires medical emergency team. a chain of events, and in the dead center of the chain is the in-hospital cardiac arrest response. 1 Edelson DP, et al. Arch Intern Med. 2008;168(10):1063–69.
3. Early defibrillation when indicated. In the hospital,
4. High-quality, minimally interrupted CPR.
the arrhythmic arrest that requires an immediate
Studies continue to show that high-quality CPR can make
diagnosis and shock is generally confined to the cardiac
the difference between survival and death.5,6,7
care unit, surgical intensive care unit, ED, or telemetry. The vast majority of resuscitations outside of these units
The 2010 Guidelines state that the use of CPR feedback
result from respiratory failure, and the need for a rapid
tools should be considered in both mock codes and
defibrillation response may be less important than
in actual rescues. Data generated by Peberdy, et al.
immediate circulatory support.
show how feedback can support the performance of compressions in target - individual compressions
In 2010 there were two lower-level studies available
delivered at the correct depth and rate, according to
comparing the use of AEDs in adults with in-hospital
Guideline recommendations.8 In a manikin study of
cardiac arrest with shockable rhythms versus manual
125 health care professionals, compressions in target
defibrillators. Both studies showed higher survival-to-
averaged 15% without feedback and 78% when
hospital discharge rates if defibrillation was provided
audiovisual feedback on compression depth and rate
through an AED program than with manual defibrillation
alone2,3. AEDs are a good alternative to facilitate early in-hospital defibrillation (goal of <3 min from collapse)4,
The importance of short pauses for pulse checks, pre-shock
especially in those areas where healthcare providers
and post-shock was demonstrated by Edelson et al 9; the
have no or limited rhythm recognition skills or where
shock success rate was 94% when a shock was delivered
they use defibrillators infrequent. Key is to support the
within 10 seconds after stopping CPR but dwindled to
AED program with an effective training and retraining
38% with a 30-second pause.
program. Enough healthcare providers should be trained to enable the first system shock to be given within 3 min
The total amount of time in CPR is also critical for a
of collapse anywhere in the hospital. Hospitals should
successful outcome. The CPR fraction, defined as the
monitor collapse-to-first shock intervals and monitor/
percentage of time that compressions are delivered
debrief resuscitation outcomes.
during a code, is an important measure of CPR
Rapid recognition of a shockable rhythm and immediate
shock delivery is critical when the presenting rhythm is coarse ventricular fibrillation (VF) or ventricular tachycardia (VT) because delays in shock delivery reduce shock efficacy. Inadvertent shocking of fine VF should be avoided as inappropriate shocks can result in asystole - a rhythm that is difficult to convert to a perfusing rhythm.
2 Zafari AM, et al. A program encouraging early defibrillation results in improved in-hospital
6 Bohn A, et al. Anaesthesist. 2011;60(7):653–660.
resuscitation efficacy. J Am Coll Cardiol 2004;44:846–52.
7 Davis DP, et al. Abstract presented at the 2009 ReSS symposium of the AHA.
3 Destro A, et al. Automatic external defibrillators in the hospital as well? Resuscitation.
8 Peberdy MA, et al. Resuscitation. 2009;80:1169–1174.
9 Edelson DP, et al. Resuscitation. 2006;71:137-145
4 Chan P, et al. Arch Intern Med. 2009;169(14)1265–73.
5 Abella BS, et al. Circulation. 2005;111:428–34.
While a CPR fraction of 50% to 60% is typical, this
6. Appropriate use of drugs and auxiliary equipment.
is not acceptable to achieve good patient outcome.
Based on expert consensus the ERC Guidelines suggest,
After implementing an Advanced Resuscitation Training
for VF/VT to give adrenaline after the third shock once
(ART) program at the University of California San Diego
chest compressions have resumed, and then to repeat
(UCSD) Medical Center, that emphasizes minimizing
every 3–5 min during cardiac arrest (alternate cycles)13.
chest compression interruption, UCSD Resuscitation Director Daniel Davis, MD, reported a 91% CPR fraction
Amiodarone 300mg is also given after the third shock.
and a doubling of survival to discharge at UCSD
CPR should not be interrupted to administer drugs13.
The Guidelines suggest that use of intraosseous
5. Controlled ventilation. Aufderheide, et al.
cannulation may speed vascular access, and use of
demonstrated that excessive ventilation (20 to 30
laryngeal airways may aid in rapid intubation.
times a minute) causes intrathoracic pressure to rise,
Transcutaneous pacing is currently only recommended
impeding cardiac filling and reducing coronary perfusion
to treat bradycardia, not asystole.
pressure10. Edelson demonstrated that the use of end-tidal CO2 was the most accurate means to track respirations
7. Consider the reversible causes of arrest. At some
during a code.11 The 2010 ERC Guidelines recommend
point in the resuscitation, time should be taken to rapidly
the use of EtCO2 for intubation verification and for
assess whether the patient may have a reversible cause
tracking of the resuscitation progress12. According to the
of arrest, such as the Hs and Ts:
current Guidelines, ventilation should be performed at a
• Hypovolemia, hypoxia, hydrogen ions (acidosis),
rate of 2 ventilations for every 30 compressions before
hyperkalemia or hypokalemia, hypothermia,
intubation, and 8 to 10 times a minute after intubation.
hyperglycemia and hypoglycemia
• Toxins, tamponade, tension pneumothorax,
Ideally, intubation should be performed without pausing
thrombosis, thromboembolism, trauma
compressions, or done during other natural pauses (for rhythm analysis or pulse checks). Delays in intubation
A checklist of signs and symptoms can be helpful.
and multiple attempts should be noted.
10 Davis DP. CEU program, A New Algorithm for CPR Training: Strengthening the
12 Edelson DP, et al. Resuscitation. 2010;81:317–322.
Chain of Survival. Medcom Trainex. 2012
13 2010 European Resuscitation Council Guidelines for Resuscitation. Resuscitation. 81 (2010)
11 Aufderheide TP, et al. Circulation. 2004 Apr 27;109(16):1960—5.
The charts below show the ERC Adult Basic Life Support (BLS) and Advanced Cardiac Life Support (ACLS) algorithms as well as the pediatric and newborn resuscitation algorithms.
Adult Basic Life Support - BLS
Resuscitation, 81 (2010) 1219-1276
Copyright European Resuscitation Council www.erc.edu 2013/024
Advanced Life Support
CPR Quality
• Push hard (=2 inches [5 cm])
and fast (=100/min) and allow
complete chest recoil
Minimize interruptions in
• Avoid excessive ventilation
• Rotate compressor every 2
• If no advanced airway, 30:2
compression-ventilation ratio
• Quantitative waveform
• If PETCO2 <10 mm Hg, attempt
to improve CPR quality
Intra-arterial pressure
• If relaxation phase (diastolic)
pressure<20 mm Hg, attempt
to improve CPR quality
Return of Spontaneous
Pulse and blood pressure
• Abrupt sustained increase in
PETCO2 (typically =40 mm Hg)
• Spontaneous arterial pressure
waves with intra-arterial
Shock Energy
• Biphasic: Manufacturer
recommendation (120-200 J);
if unknown, use maximum
available. Second and
subsequent doses should be
equivalent, and higher doses
may be considered.
• Monophasic: 360 J
Drug Therapy
• Adrenaline IV/IO Dose:
1 mg after the third shock
repeat every 3-5 minutes
• Amiodarone IV/IO Dose:
First dose: 300 mg bolus.
Second dose: 150 mg.
Advanced Airway
• Supraglottic advanced airway
or endotracheal intubation
• Waveform capnography to
confirm and monitor ET tube
• 8-10 breaths per minute with
continuous chest compressions
Resuscitation, 81 (2010) 1219-1276
Copyright European Resuscitation Council www.erc.edu 2013/024
Pediatric Advanced Life Support
CPR Quality
• Push hard (=1/3 of anterior-
posterior diameter of chest)
and fast (at least 100/min) and
allow complete chest recoil
Minimize interruptions in
• Avoid excessive ventilation
• Rotate compressor every 2
• If no advanced airway, 15:2
compression-ventilation
ratio. If advanced airway,
8-10 breaths per minute with
continuous chest compressions
Shock Energy for
• First shock 4 J/kg, subsequent
shocks =4 J/kg, maximum 10
J/kg or adult dose.
Drug Therapy
• Adrenaline IO/IV Dose:
0.01 mg/kg (0.1 mL/kg of 1:10
000 concentration) after the
third shock. Repeat every 3-5
minutes. If no IO/IV access,
may give endotracheal dose:
0.1 mg/kg (0.1 mL/kg of 1:1000
• Amiodarone IO/IV Dose: 5
mg/kg bolus during cardiac
arrest. May repeat up to
2 times for refractory VF/
Advanced Airway
• Endotracheal intubation or
supraglottic advanced airway
• Waveform capnography or
capnometry to confirm and
monitor ET tube placement
• Once advanced airway in
place give 1 breath every 6-8
seconds (8-10 breaths per
Return of Spontaneous
Circulation (ROSC)
Pulse and blood pressure
• Spontaneous arterial pressure
waves with intra-arterial
Resuscitation, 81 (2010) 1219-1276
Copyright European Resuscitation Council www.erc.edu 2013/024
Newborn Life Support
Resuscitation, 81 (2010) 1219-1276
Copyright European Resuscitation Council www.erc.edu 2013/024
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